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  • Conformal nanocarbon coating of alumina nanocrystals for biosensing and bioimaging

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    Ostrikov183508-Accepted.pdf (988.5Kb)
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    Accepted Manuscript (AM)
    Author(s)
    Aramesh, Morteza
    Tran, Phong A
    Ostrikov, Kostya Ken
    Prawer, Steven
    Griffith University Author(s)
    Ostrikov, Ken
    Year published
    2017
    Metadata
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    Abstract
    A conformal coating technique with nanocarbon was developed to enhance the surface properties of alumina nanoparticles for bio-applications. The ultra-thin carbon layer induces new surface properties such as water dispersion, cytocompatibility and tuneable surface chemistry, while maintaining the optical properties of the core particle. The possibility of using these particles as agents for DNA sensing was demonstrated in a competitive assay. Additionally, the inherent fluorescence of the core alumina particles provided a unique platform for localization and monitoring of living organisms, allowing simultaneous cell monitoring ...
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    A conformal coating technique with nanocarbon was developed to enhance the surface properties of alumina nanoparticles for bio-applications. The ultra-thin carbon layer induces new surface properties such as water dispersion, cytocompatibility and tuneable surface chemistry, while maintaining the optical properties of the core particle. The possibility of using these particles as agents for DNA sensing was demonstrated in a competitive assay. Additionally, the inherent fluorescence of the core alumina particles provided a unique platform for localization and monitoring of living organisms, allowing simultaneous cell monitoring and intra-cellular sensing. Nanoparticles were able to carry genes to the cells and release them in an environment where specific biomarkers were present.
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    Journal Title
    Carbon
    Volume
    122
    DOI
    https://doi.org/10.1016/j.carbon.2017.06.101
    Copyright Statement
    © 2017 Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
    Subject
    Physical sciences
    Chemical sciences
    Engineering
    Science & Technology
    Chemistry, Physical
    Materials Science, Multidisciplinary
    Publication URI
    http://hdl.handle.net/10072/401992
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    • Journal articles

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