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dc.contributor.authorBurrell, AJC
dc.contributor.authorNeto, AS
dc.contributor.authorTrapani, T
dc.contributor.authorBroadley, T
dc.contributor.authorFrench, C
dc.contributor.authorUdy, AA
dc.contributor.authorVisser, A
dc.contributor.authorMattke, A
dc.contributor.authorRegli, A
dc.contributor.authorRashid, A
dc.contributor.authorTabah, A
dc.contributor.authorRichards, B
dc.contributor.authorWhite, H
dc.contributor.authorLister, P
dc.contributor.authoret al.
dc.date.accessioned2021-02-22T03:53:31Z
dc.date.available2021-02-22T03:53:31Z
dc.date.issued2021
dc.identifier.issn1073-449X
dc.identifier.doi10.1164/rccm.202009-3661LE
dc.identifier.urihttp://hdl.handle.net/10072/402452
dc.description.abstractTo the Editor: The global coronavirus disease (COVID-19) pandemic has seen a significant increase in the use of preprint services to enable the widespread dissemination of research findings (1). However, whether such facilities influence practice change is currently unknown. Here, we describe the impact of the preprint release and eventual publication of the RECOVERY (Randomised Evaluation of COVID-19 Therapy) trial (2) on corticosteroid use in clinical practice in Australian ICUs. The RECOVERY trial tested the efficacy of dexamethasone (6 mg by mouth or intravenously for up to 10 d) in hospitalized patients with clinically suspected or confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and demonstrated a reduction in 28-day mortality, particularly in those receiving either mechanical ventilation or oxygen. Before these results, the Australian and New Zealand Intensive Care Society COVID-19 guidelines recommended against the routine use of corticosteroids (3).
dc.description.peerreviewedYes
dc.languageeng
dc.publisherAmerican Thoracic Society
dc.relation.ispartofpagefrom368
dc.relation.ispartofpageto371
dc.relation.ispartofissue3
dc.relation.ispartofjournalAmerican Journal of Respiratory and Critical Care Medicine
dc.relation.ispartofvolume203
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchCardiovascular medicine and haematology
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode3201
dc.subject.fieldofresearchcode3202
dc.titleRapid translation of COVID-19 preprint data into critical care practice
dc.typeJournal article
dc.type.descriptionC2 - Articles (Other)
dcterms.bibliographicCitationBurrell, et al., Rapid translation of COVID-19 preprint data into critical care practice, American Journal of Respiratory and Critical Care Medicine, 2021, 203 (3), pp. 368-371
dcterms.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.date.updated2021-02-22T03:31:46Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© The Author(s) 2021. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International (CC BY-NC-ND 4.0) License, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorCorley, Amanda


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