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dc.contributor.authorKrishna, Sneha
dc.contributor.authorDavoren, Peter
dc.date.accessioned2021-03-09T02:37:44Z
dc.date.available2021-03-09T02:37:44Z
dc.date.issued2021
dc.identifier.issn0026-0495en_US
dc.identifier.doi10.1016/j.metabol.2020.154485en_US
dc.identifier.urihttp://hdl.handle.net/10072/402979
dc.description.abstractBackground: Hypertriglyceridaemia is an oft-forgotten cause of acute pancreatitis, which can lead to delayed appropriate therapy and increased morbidity. Uncontrolled diabetes and acute alcohol ingestion can exacerbate this. There are no definite guidelines on management, and there is limited evidence supporting current treatment methods. Objective: A two-centre retrospective audit was conducted of acute pancreatitis presentations over three-years, and management reviewed of those with elevated triglyceride levels (≥6mmol/L). Results: Of 1628 presentations of pancreatitis between 01- Jan-2016 to 31-Dec-2018 to either Gold Coast University Hospital or Robina Hospital, 27 presentations (1.64%) from 20 patients are attributed to hypertriglyceridaemia on admission (mean 67.4mmol/L). 92.6% required admission into hospital (mean 11.5day). 36% had insulin infusion, 12% had apheresis, and 28% required intensive care admission. Only 84% were discharged on statins and/or fibrates. 72% of patients had further episodes hypertriglyceridaemia-induced pancreatitis. Pre-existing diabetes affected 44%, and HbA1c was measured in only 63.6% of these. Acute alcohol intake was relevant for 22.2% of presentations. Endocrinologist opinion was sought in 51.8%. Conclusion: Whilst hypertriglyceridaemia-induced pancreatitis is uncommon, it is undertreated and specialist opinion under-utilised. This increases risk of recurrence, morbidity, and further hospital presentations.en_US
dc.languageEnglishen_US
dc.publisherElsevieren_US
dc.relation.ispartofconferencename18th Annual World Congress on Insulin Resistance Diabetes & Cardiovascular Diseaseen_US
dc.relation.ispartofconferencetitleMetabolismen_US
dc.relation.ispartofdatefrom2020-12-03
dc.relation.ispartofdateto2020-12-05
dc.relation.ispartoflocationLos Angeles, USAen_US
dc.relation.ispartofpagefrom8en_US
dc.relation.ispartofpageto8en_US
dc.relation.ispartofvolume116en_US
dc.subject.fieldofresearchClinical Sciencesen_US
dc.subject.fieldofresearchcode1103en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsLife Sciences & Biomedicineen_US
dc.subject.keywordsEndocrinology & Metabolismen_US
dc.subject.keywordshyperlipidaemiaen_US
dc.subject.keywordshypertriglyceridaemiaen_US
dc.titleA Three-year Review of the Management of Hypertriglyceridaemia-induced Pancreatitisen_US
dc.typeConference outputen_US
dc.type.descriptionE3 - Conferences (Extract Paper)en_US
dcterms.bibliographicCitationKrishna, S; Davoren, P, A Three-year Review of the Management of Hypertriglyceridaemia-induced Pancreatitis, Metabolism, 2021, 116, pp. 8-8en_US
dc.date.updated2021-03-08T02:00:01Z
gro.hasfulltextNo Full Text
gro.griffith.authorDavoren, Peter M.


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