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  • MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy

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    Nair475701-Published.pdf (134.2Kb)
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    Version of Record (VoR)
    Author(s)
    Elad, Sharon
    Cheng, Karis Kin Fong
    Lalla, Rajesh V
    Yarom, Noam
    Hong, Catherine
    Logan, Richard M
    Bowen, Joanne
    Gibson, Rachel
    Saunders, Deborah P
    Zadik, Yehuda
    Ariyawardana, Anura
    Correa, Maria Elvira
    Ranna, Vinisha
    Bossi, Paolo
    Nair, Raj
    et al.
    Griffith University Author(s)
    Nair, Raj
    Year published
    2020
    Metadata
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    Abstract
    Background: Mucositis is a significant toxicity of cancer therapy with numerous systemic sequelae. The goal of this systematic review was to update the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) Clinical Practice Guidelines for the management of mucositis. Methods: The literature was reviewed systematically to identify interventions for mucositis. Studies were rated according to the presence of major and minor flaws according to previously published criteria. The body of evidence for each intervention and in each treatment setting was assigned a level of ...
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    Background: Mucositis is a significant toxicity of cancer therapy with numerous systemic sequelae. The goal of this systematic review was to update the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) Clinical Practice Guidelines for the management of mucositis. Methods: The literature was reviewed systematically to identify interventions for mucositis. Studies were rated according to the presence of major and minor flaws according to previously published criteria. The body of evidence for each intervention and in each treatment setting was assigned a level of evidence based on previously published criteria. Guidelines were developed based on the level of evidence, with 3 possible guideline determinations: recommendation, suggestion, or no guideline possible. Results: The guideline covers evidence from 1197 publications related to oral or gastrointestinal mucositis. Thirteen new guidelines were developed for or against the use of various interventions in specific treatment settings, and 11 previous guidelines were confirmed after aa review of new evidence. Thirteen previously established guidelines were carried over because there was no new evidence for these interventions. Conclusions: The updated MASCC/ISOO Clinical Practice Guidelines for mucositis provide professional health caregivers with a clinical setting-specific, evidence-based tool to help with the management of mucositis in patients who have cancer.
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    Journal Title
    Cancer
    Volume
    126
    Issue
    19
    DOI
    https://doi.org/10.1002/cncr.33100
    Copyright Statement
    © 2020 The Authors. Cancer published by Wiley Periodicals LLC on behalf of American Cancer Society. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
    Subject
    Oncology and Carcinogenesis
    Public Health and Health Services
    Science & Technology
    Life Sciences & Biomedicine
    cancer
    gastrointestinal
    Publication URI
    http://hdl.handle.net/10072/403504
    Collection
    • Journal articles

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