Current treatment strategies in rheumatoid arthritis after methotrexate are not enough to maintain sustained remission: There is no holy grail!

Abstract

The ideal state for a patient with rheumatoid arthritis (RA) is sustained remission. Contemporary treatment strategies such as early initiation of DMARD(s), optimal methotrexate dosing and treating to a target with validated outcomes have improved the likelihood of remission in RA. Remission, however defined, is not always achieved and even less often will patients with RA maintain sustained remission over time.