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  • Comparing multi-attribute utility instruments: CP-6D, a Cerebral palsy specific instrument, vs AQoL-4D

    Author(s)
    Bahrampour, Mina
    Downes, Martin
    Scuffham, Paul A
    Byrnes, Joshua
    Griffith University Author(s)
    Scuffham, Paul A.
    Byrnes, Joshua M.
    Downes, Martin J.
    Bahrampour, Mina
    Year published
    2021
    Metadata
    Show full item record
    Abstract
    BACKGROUND: Economic-evaluations of Cerebral palsy (CP) were based on utility estimates of health-related quality of life (HRQoL) from generic multi-attribute utility instruments (MAUIs). However, generic instruments had limited use as they could not capture some of the important aspects of living with CP. The Cerebral palsy 6 Dimension (CP-6D) is a disease specific MAUI. In this study, we compared the results of CP-6D with the Assessment of Quality of Life (AQoL-4D), a generic MAUI, and tested the criterion validity of the CP-6D in the general population. METHODS: An online survey of the Australian general population (n=2002), ...
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    BACKGROUND: Economic-evaluations of Cerebral palsy (CP) were based on utility estimates of health-related quality of life (HRQoL) from generic multi-attribute utility instruments (MAUIs). However, generic instruments had limited use as they could not capture some of the important aspects of living with CP. The Cerebral palsy 6 Dimension (CP-6D) is a disease specific MAUI. In this study, we compared the results of CP-6D with the Assessment of Quality of Life (AQoL-4D), a generic MAUI, and tested the criterion validity of the CP-6D in the general population. METHODS: An online survey of the Australian general population (n=2002), who completed both the AQoL-4D and CP-6D MAUIs, was conducted. Validity was assessed from the correlations between the domains, items and instruments. ANOVA and t-tests were used to assess the instrument's discrimination in different social demographic categories. RESULTS: There was a moderate correlation between the instruments (0.64). Differences in socio-demographic characteristics showed a medium effect size (p <0.001) in both instruments and had a similar effect on utility weights in both instruments. Although, the CP-6D was more sensitive to changes in income and education. CONCLUSIONS: Our results suggest that CP-6D and AQoL-4D were measuring a similar underlying construct. Both instruments responded similarly to socio-demographic differences.
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    Journal Title
    Expert Review of Pharmacoeconomics & Outcomes Research
    DOI
    https://doi.org/10.1080/14737167.2021.1909477
    Note
    This publication has been entered as an advanced online version in Griffith Research Online.
    Subject
    Pharmacology and Pharmaceutical Sciences
    Public Health and Health Services
    Applied Economics
    AQoL-4D
    CP-6D
    Utility
    cerebral palsy
    health related quality of life
    Publication URI
    http://hdl.handle.net/10072/403555
    Collection
    • Journal articles

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