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  • The Course and Predictors of Quality of Life in Nursing Home Residents with Young-onset Dementia

    Author(s)
    Pu, Lihui
    Bakker, Christian
    Appelhof, Britt
    Van Duinen-van den Ijssel, Jeannette CL
    Zwijsen, Sandra A
    Teerenstra, Steven
    Smalbrugge, Martin
    Verhey, Frans RJ
    de Vugt, Marjolein E
    Zuidema, Sytse U
    Koopmans, Raymond TCM
    Griffith University Author(s)
    Pu, Lihui
    Year published
    2020
    Metadata
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    Abstract
    Background: People with young-onset dementia (YOD) living in nursing homes may experience poor quality of life (QoL) due to advanced dementia, high prevalence of neuropsychiatric symptoms and psychotropic drug use. However, the course of QoL in institutionalized people with YOD and factors that predict this course are unclear. This knowledge could help health professionals identify appropriate interventions to improve QoL in YOD. Objective: To explore the course of QoL in institutionalized people with YOD and resident-related predictors of that course. Methods: Secondary analyses were conducted with longitudinal data from ...
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    Background: People with young-onset dementia (YOD) living in nursing homes may experience poor quality of life (QoL) due to advanced dementia, high prevalence of neuropsychiatric symptoms and psychotropic drug use. However, the course of QoL in institutionalized people with YOD and factors that predict this course are unclear. This knowledge could help health professionals identify appropriate interventions to improve QoL in YOD. Objective: To explore the course of QoL in institutionalized people with YOD and resident-related predictors of that course. Methods: Secondary analyses were conducted with longitudinal data from the Behavior and Evolution in Young-ONset Dementia (BEYOND)-II study. A total of 278 people with YOD were recruited from 13 YOD special care units in the Netherlands. QoL was measured by the proxy assessment of Quality of Life in Dementia (QUALIDEM) questionnaire at four assessments over 18 months. Independent variables included age, gender, dementia subtype, length of stay, dementia severity, neuropsychiatric symptoms and psychotropic drug use at baseline. Multilevel modeling adjusted for correlation within nursing homes and residents was used to determine the course and predictors of QoL. Results: The total QUALIDEM score (range: 0–111) decreased over 18 months with a statistically significant decline of 0.73 points per six months. A significant increase of QoL over time was seen in the subscales “Care relationship”, “Positive self-image”, and “Feeling at home”. However, a significant decline was observed in the subscales “Positive affect”, “Social relations”, and “Something to do”. Residents’ course of QoL was positively associated with the baseline scores of the QoL, age and longer duration of stay; however, being male, having advanced dementia, Alzheimer’s disease and high rates of neuropsychiatric symptoms at baseline were negatively associated with the course of QoL Conclusion: Longitudinal changes in QoL in residents with YOD were small over 18 months and QUALIDEM subscales showed multidirectional changes. The largest QoL decline in the subscale “Positive affect” suggests that interventions should be targeted to improve positive emotions, in particular for male residents with neuropsychiatric symptoms and advanced dementia.
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    Conference Title
    International Psychogeriatrics
    Volume
    32
    Issue
    S1
    DOI
    https://doi.org/10.1017/S1041610220002276
    Subject
    Biomedical and clinical sciences
    Psychology
    Social Sciences
    Science & Technology
    Life Sciences & Biomedicine
    Psychology, Clinical
    Geriatrics & Gerontology
    Publication URI
    http://hdl.handle.net/10072/404378
    Collection
    • Conference outputs

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