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dc.contributor.authorFerreira, Elaine Barros
dc.contributor.authorVasques, Christiane Inocencio
dc.contributor.authorGadia, Rafael
dc.contributor.authorChan, Raymond Javan
dc.contributor.authorSilva Guerra, Eliete Neves
dc.contributor.authorMezzomo, Luis Andre
dc.contributor.authorCanto, Graziela De Luca
dc.contributor.authorDiniz dos Reis, Paula Elaine
dc.date.accessioned2021-05-19T23:48:12Z
dc.date.available2021-05-19T23:48:12Z
dc.date.issued2017
dc.identifier.issn0941-4355en_US
dc.identifier.doi10.1007/s00520-016-3521-7en_US
dc.identifier.urihttp://hdl.handle.net/10072/404505
dc.description.abstractPurpose: The purpose of the study is to evaluate the effects of pharmacological and non-pharmacological topical controls in the prevention of radiation dermatitis. Methods: Relevant clinical trials were identified through electronic searching databases CINAHL, CENTRAL, LILACS, PubMed, Scopus, and Web of Science. Handsearching and gray literature searches were also performed to find additional references. Primary outcomes of interest were the development of radiation dermatitis and the time of occurrence of radiation dermatitis. Results: Thirteen randomized clinical trials were included in this review. The trials were published in Chinese, English, or French, from 1980 to 2015. Pharmacological interventions used in the trials were trolamine, aloe vera, allantoin, Lianbai liquid, sucralfate, Na-sucrose octasulfate, olive oil, hialuronic acid, and dexpanthenol. Non-pharmacological topical controls were usual care/institution routine, aqueous cream, mild soap, water thermal gel, placebo, and no intervention. Conclusions: There was no strong evidence that indicates differences between topical pharmacological interventions or non-pharmacological topical controls in the prevention of acute radiation dermatitis among patients with head and neck cancer undergoing radiotherapy.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherSpringeren_US
dc.relation.ispartofpagefrom1001en_US
dc.relation.ispartofpageto1011en_US
dc.relation.ispartofissue3en_US
dc.relation.ispartofjournalSupportive Care in Canceren_US
dc.relation.ispartofvolume25en_US
dc.subject.fieldofresearchMedical and Health Sciencesen_US
dc.subject.fieldofresearchPsychology and Cognitive Sciencesen_US
dc.subject.fieldofresearchcode11en_US
dc.subject.fieldofresearchcode17en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsLife Sciences & Biomedicineen_US
dc.subject.keywordsOncologyen_US
dc.subject.keywordsHealth Care Sciences & Servicesen_US
dc.subject.keywordsRehabilitationen_US
dc.titleTopical interventions to prevent acute radiation dermatitis in head and neck cancer patients: a systematic reviewen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationFerreira, EB; Vasques, CI; Gadia, R; Chan, RJ; Silva Guerra, EN; Mezzomo, LA; Canto, GDL; Diniz dos Reis, PE, Topical interventions to prevent acute radiation dermatitis in head and neck cancer patients: a systematic review, Supportive Care in Cancer, 2017, 25 (3), pp. 1001-1011en_US
dcterms.dateAccepted2016-12-05
dc.date.updated2021-05-19T23:45:26Z
dc.description.versionAccepted Manuscript (AM)en_US
gro.rights.copyright© 2017 Springer Berlin/Heidelberg. This is an electronic version of an article published in Supportive Care in Cancer, 2017, 25 (3), pp. 1001-1011. Supportive Care in Cancer is available online at: http://link.springer.com/ with the open URL of your article.en_US
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gro.griffith.authorChan, Ray


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