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dc.contributor.authorYu, Xue Qin
dc.contributor.authorDasgupta, Paramita
dc.contributor.authorKahn, Clare
dc.contributor.authorKou, Kou
dc.contributor.authorCramb, Susanna
dc.contributor.authorBaade, Peter
dc.date.accessioned2021-05-27T04:56:26Z
dc.date.available2021-05-27T04:56:26Z
dc.date.issued2021
dc.identifier.issn2045-7634
dc.identifier.doi10.1002/cam4.3844
dc.identifier.urihttp://hdl.handle.net/10072/404717
dc.description.abstractBackground: To estimate trends in the crude probability of death for cancer patients by sex, age and spread of disease over the past 30 years in New South Wales, Australia. Methods: Population-based cohort of 716,501 people aged 15–89 years diagnosed with a first primary cancer during 1985–2014 were followed up to 31 December 2015. Flexible parametric relative survival models were used to estimate the age-specific crude probability of dying from cancer and other causes by calendar year, sex and spread of disease for all solid tumours combined and cancers of the colorectum, lung, female breast, prostate and melanoma. Results: Estimated 10-year sex, age and spread-specific crude probabilities of cancer death generally decreased over time for most cancer types, although the magnitude of the decrease varied. For example, out of 100 fifty-year old men with localized prostate cancer, 12 would have died from their cancer if diagnosed in 1985 and 3 in 2014. Greater degree of spread was consistently associated with higher probability of dying from cancer, although outcomes for lung cancer were consistently poor. For both males and females, the probability of non-cancer deaths was higher among older patients, those diagnosed with localized cancers and where cancer survival was higher. Conclusion: Crude probabilities presented here may be useful in helping clinicians and their patients better understand prognoses and make informed decisions about treatment. They also provide novel insights into the relative contributions that early detection and improved treatments have on the observed temporal patterns in cancer survival.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherWiley
dc.relation.ispartofjournalCancer Medicine
dc.subject.fieldofresearchBiochemistry and Cell Biology
dc.subject.fieldofresearchOncology and Carcinogenesis
dc.subject.fieldofresearchcode0601
dc.subject.fieldofresearchcode1112
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsOncology
dc.subject.keywordscancer
dc.subject.keywordscompeting risks
dc.titleCrude probability of death for cancer patients by spread of disease in New South Wales, Australia 1985 to 2014
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationYu, XQ; Dasgupta, P; Kahn, C; Kou, K; Cramb, S; Baade, P, Crude probability of death for cancer patients by spread of disease in New South Wales, Australia 1985 to 2014, Cancer Medicine, 2021
dcterms.dateAccepted2021-02-23
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.date.updated2021-05-27T00:54:17Z
dc.description.versionVersion of Record (VoR)
gro.description.notepublicThis publication has been entered as an advanced online version in Griffith Research Online.
gro.rights.copyright© 2021 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorDasgupta, Paramita
gro.griffith.authorBaade, Peter D.


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