Show simple item record

dc.contributor.authorBarillot, Celia
dc.contributor.authorCock, Ian Edwin
dc.date.accessioned2021-06-02T00:21:43Z
dc.date.available2021-06-02T00:21:43Z
dc.date.issued2021
dc.identifier.issn2249-0159
dc.identifier.doi10.5530/pc.2021.2.17
dc.identifier.urihttp://hdl.handle.net/10072/404817
dc.description.abstractIntroduction: Kunzea ambigua (Sm.) Druce and Kunzea flavescens C.T. White and W.D. Francis are endemic Australian plants. Decoctions, infusions and essential oils produced from the leaves were used traditionally to treat a variety of bacterial diseases. Despite this, these species have not been rigorously examined for antibacterial properties against many pathogens. Methods: The antimicrobial activity of K. ambigua and K. flavescens essential oils and a K. ambigua hydrosol was investigated by disc diffusion and liquid dilution MIC assays against a panel of pathogenic bacteria. Toxicity was determined using the Artemia franciscana nauplii bioassay. Results: K. ambigua and K. flavescens essential oils displayed noteworthy growth inhibitory activity against A. baylyi, K. pneumonia, P. mirabilis and P. aeruginosa (MIC values substantially <1000μg/mL). Indeed, MIC values as low as 33μg/mL were noted against P. aeruginosa. Noteworthy growth inhibitory activity was also noted for the K. ambigua hydrosol against A. baylyi and P. aeruginosa. All extracts were determined to be non-toxic in the Artemia franciscana nauplii bioassay, indicating their safety for internal use as well as for topical uses. Conclusion: The lack of toxicity of the Kunzea spp. extracts and their growth inhibitory bioactivity against a panel of pathogenic bacteria partially validate the traditional usage of these species to treat bacterial diseases and indicate their potential in the development of antiseptic agents.
dc.description.peerreviewedYes
dc.publisherPharmacognosy Network Worldwide
dc.relation.ispartofpagefrom81
dc.relation.ispartofpageto87
dc.relation.ispartofissue2
dc.relation.ispartofjournalPharmacognosy Communications
dc.relation.ispartofvolume11
dc.subject.fieldofresearchPlant Biology
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciences
dc.subject.fieldofresearchcode0607
dc.subject.fieldofresearchcode1115
dc.titleKunzea ambigua (Sm.) Druce and Kunzea flavescens C.T. White and W.D. Francis Essential Oils Inhibit the Growth of Some Bacterial Triggers of Inflammatory Diseases
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationBarillot, C; Cock, IE, Kunzea ambigua (Sm.) Druce and Kunzea flavescens C.T. White and W.D. Francis Essential Oils Inhibit the Growth of Some Bacterial Triggers of Inflammatory Diseases, Pharmacognosy Communications, 2021, 11 (2), pp. 81-87
dcterms.licensehttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.date.updated2021-06-01T20:59:34Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© The Author(s) 2021. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International (CC BY-NC-ND 4.0) License (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorCock, Ian E.


Files in this item

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record