Show simple item record

dc.contributor.authorMpala, Lindiwe
dc.contributor.authorChikowe, Getmore
dc.contributor.authorEdwin Cock, Ian
dc.date.accessioned2021-06-02T01:22:41Z
dc.date.available2021-06-02T01:22:41Z
dc.date.issued2020
dc.identifier.issn2249-0159
dc.identifier.doi10.5530/pc.2020.3.23
dc.identifier.urihttp://hdl.handle.net/10072/404834
dc.description.abstractIntroduction: High antioxidant levels have been linked with multiple therapeutic properties, including antibacterial activity. Therefore, high antioxidant plant preparations are good targets for antibacterial testing. D. pruriens has high antioxidant capacity although it is yet to be tested for the ability to inhibit the growth of bacterial pathogens. Methods: The ability of D. pruriens fruit and leaf extracts to inhibit the growth of a panel of bacterial and fungal pathogens was investigated by disc diffusion assay. Toxicity was examined using the Artemia franciscana nauplii bioassay. Results: All D. pruriens fruit and leaf extracts were completely ineffective at inhibiting the growth of gram-positive and gram-negative panels of bacteria, as well as fungi. The extracts were non-toxic in the Artemia bioassay following 24 h exposure. Conclusion: Despite their high antioxidant capacity, D. pruriens fruit and leaf extracts were completely ineffective bacterial and fungal growth inhibitors. However, these extracts may have other therapeutic properties and testing against protozoa, virus and tumour cells is required.
dc.description.peerreviewedYes
dc.publisherPharmacognosy Network Worldwide
dc.relation.ispartofpagefrom113
dc.relation.ispartofpageto118
dc.relation.ispartofissue3
dc.relation.ispartofjournalPharmacognosy Communications
dc.relation.ispartofvolume10
dc.subject.fieldofresearchPlant Biology
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciences
dc.subject.fieldofresearchcode0607
dc.subject.fieldofresearchcode1115
dc.titleDavidsonia pruriens F. Muell. Fruit and Leaf Extracts Lack Antibacterial and Antifungal Activity
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationMpala, L; Chikowe, G; Edwin Cock, I, Davidsonia pruriens F. Muell. Fruit and Leaf Extracts Lack Antibacterial and Antifungal Activity, Pharmacognosy Communications, 2020, 10 (3), pp. 113-118
dcterms.licensehttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.date.updated2021-06-01T21:43:26Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© The Author(s) 2020. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International (CC BY-NC-ND 4.0) License (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorCock, Ian E.
gro.griffith.authorMpala, Lindiwe N.
gro.griffith.authorChikowe, Getmore R.


Files in this item

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record