Show simple item record

dc.contributor.authorWright, Mitchell Henry
dc.contributor.authorWood, Aiden
dc.contributor.authorGreene, Anthony Carlson
dc.contributor.authorCock, Ian Edwin
dc.date.accessioned2021-06-02T05:54:19Z
dc.date.available2021-06-02T05:54:19Z
dc.date.issued2020
dc.identifier.issn2249-0159
dc.identifier.doi10.5530/pc.2020.2.18
dc.identifier.urihttp://hdl.handle.net/10072/404873
dc.description.abstractIntroduction: Acronychia acidula F. Muell. (lemon aspen, pigeon berry) has been previously recognized for its antimicrobial properties against a broad panel of pathogenic bacteria. This study assessed the effectiveness of A. acidula as an inhibitory agent against bacteria associated with malodour formation. Methodology: A. acidula fruit extracts were prepared using methanol or water as the extraction solvent. Growth inhibition and minimal inhibitory concentrations were determined against C. jeikeium, P. acnes and B. linens through disc diffusion assays. MIC values were quantified to evaluate their efficacies as antimicrobials. Toxicity of each extract was determined using the Artemia franciscana nauplii bioassay. Results: A. acidula aqueous fruit extracts inhibited the growth of B. linens (MIC = 1258 μg/mL), C. jeikeium (MIC = 1630 μg/mL) and P. acnes (MIC = 1455 μg/mL) in the disc diffusion assay. Similarly, the methanolic fruit extracts inhibited the growth of B. linens (MIC = 2608 μg/mL) and C. jeikeium (MIC = 3044 μg/mL), although no growth inhibition of P. acnes was observed. Both aqueous and methanolic A. acidula extracts were nontoxic towards Artemia nauplii (LC50 values of 1872 μg/mL and 1500 μg/mL). Conclusion: A. acidula fruit extracts were non-toxic and also displayed moderate growth inhibitory bioactivity against B. linens, C. jeikeium and P. acnes, highlighting their potential as additives to deodorants.
dc.description.peerreviewedYes
dc.publisherPharmacognosy Network Worldwide
dc.relation.ispartofpagefrom95
dc.relation.ispartofpageto101
dc.relation.ispartofissue2
dc.relation.ispartofjournalPharmacognosy Communications
dc.relation.ispartofvolume10
dc.subject.fieldofresearchPlant Biology
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciences
dc.subject.fieldofresearchcode0607
dc.subject.fieldofresearchcode1115
dc.titleGrowth Inhibitory Activity of Acronychia acidula F. Muell. Fruit Extracts Towards Malodour-forming Bacteria
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationWright, MH; Wood, A; Greene, AC; Cock, IE, Growth Inhibitory Activity of Acronychia acidula F. Muell. Fruit Extracts Towards Malodour-forming Bacteria, Pharmacognosy Communications, 2020, 10 (2), pp. 95-101
dcterms.licensehttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.date.updated2021-06-02T05:53:02Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© The Author(s) 2020. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International (CC BY-NC-ND 4.0) License (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorCock, Ian E.
gro.griffith.authorGreene, Tony C.
gro.griffith.authorWright, Mitchell H.


Files in this item

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record