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dc.contributor.authorIslam, Kamrul
dc.contributor.authorHeffernan, Aaron J
dc.contributor.authorNaicker, Saiyuri
dc.contributor.authorHenderson, Andrew
dc.contributor.authorHassen Chowdhury, Mohammed Abdul
dc.contributor.authorRoberts, Jason A
dc.contributor.authorSime, Fekade B
dc.date.accessioned2021-06-10T00:33:08Z
dc.date.available2021-06-10T00:33:08Z
dc.date.issued2021
dc.identifier.issn1746-0913en_US
dc.identifier.doi10.2217/fmb-2020-0193en_US
dc.identifier.urihttp://hdl.handle.net/10072/405050
dc.description.abstractAim: To determine the prevalence of extended-spectrum β-lactamase (ESBL) and metallo-β-lactamase (MBL)-producing Escherichia coli in South Asia. Methodology: A systematic review and meta-analysis of data published in PubMed, EMBASE, Web of Science and Scopus. Results: The pooled prevalence of ESBL and MBL-producing E. coli in South Asia were 33% (95% CI: 27-40%) and 17% (95% CI: 12-24%), respectively. The prevalence of bla CTX-M type was 58% (95% CI: 49-66%) with blaCTX-M-15 being the most prevalent (51%, 95% CI: 40-62%) variant. The most prevalent MBL variant was blaNDM-1 (33%, 95% CI: 20-50%). Conclusion: This study suggests a high prevalence of ESBLs and MBLs among E. coli clinical isolates. Comprehensive resistance surveillance is required to guide clinicians prescribing antibiotics in South Asia.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherFuture Medicineen_US
dc.relation.ispartofpagefrom521en_US
dc.relation.ispartofpageto535en_US
dc.relation.ispartofissue7en_US
dc.relation.ispartofjournalFuture Microbiologyen_US
dc.relation.ispartofvolume16en_US
dc.subject.fieldofresearchMicrobiologyen_US
dc.subject.fieldofresearchMedical Microbiologyen_US
dc.subject.fieldofresearchcode0605en_US
dc.subject.fieldofresearchcode1108en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsLife Sciences & Biomedicineen_US
dc.subject.keywordsEscherichia colien_US
dc.subject.keywordsextended-spectrum &#946en_US
dc.titleEpidemiology of extended-spectrum β-lactamase and metallo-β-lactamase-producing Escherichia coli in South Asiaen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationIslam, K; Heffernan, AJ; Naicker, S; Henderson, A; Hassen Chowdhury, MA; Roberts, JA; Sime, FB, Epidemiology of extended-spectrum β-lactamase and metallo-β-lactamase-producing Escherichia coli in South Asia, Future Microbiology, 2021, 16 (7), pp. 521-535en_US
dc.date.updated2021-06-09T06:21:16Z
gro.hasfulltextNo Full Text
gro.griffith.authorHeffernan, Aaron J.


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