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  • Arthritogenic Alphavirus Capsid Protein

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    Author(s)
    Rao, Shambhavi
    Taylor, Adam
    Griffith University Author(s)
    Taylor, Adam
    Year published
    2021
    Metadata
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    Abstract
    In the past two decades Old World and arthritogenic alphavirus have been responsible for epidemics of polyarthritis, causing high morbidity and becoming a major public health concern. The multifunctional arthritogenic alphavirus capsid protein is crucial for viral infection. Capsid protein has roles in genome encapsulation, budding and virion assembly. Its role in multiple infection processes makes capsid protein an attractive target to exploit in combating alphaviral infection. In this review, we summarize the function of arthritogenic alphavirus capsid protein, and describe studies that have used capsid protein to develop ...
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    In the past two decades Old World and arthritogenic alphavirus have been responsible for epidemics of polyarthritis, causing high morbidity and becoming a major public health concern. The multifunctional arthritogenic alphavirus capsid protein is crucial for viral infection. Capsid protein has roles in genome encapsulation, budding and virion assembly. Its role in multiple infection processes makes capsid protein an attractive target to exploit in combating alphaviral infection. In this review, we summarize the function of arthritogenic alphavirus capsid protein, and describe studies that have used capsid protein to develop novel arthritogenic alphavirus therapeutic and diagnostic strategies.
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    Journal Title
    Life
    Volume
    11
    Issue
    3
    DOI
    https://doi.org/10.3390/life11030230
    Copyright Statement
    © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
    Subject
    Clinical sciences
    Science & Technology
    Life Sciences & Biomedicine
    Biology
    Microbiology
    Life Sciences & Biomedicine - Other Topics
    Publication URI
    http://hdl.handle.net/10072/405241
    Collection
    • Journal articles

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