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dc.contributor.authorScott, Holly
dc.contributor.authorBarton, Matthew J
dc.contributor.authorJohnston, Amy NB
dc.date.accessioned2021-06-22T04:21:24Z
dc.date.available2021-06-22T04:21:24Z
dc.date.issued2021
dc.identifier.issn2056-5909
dc.identifier.doi10.1186/s40885-021-00169-z
dc.identifier.urihttp://hdl.handle.net/10072/405265
dc.description.abstractIsolated systolic hypertension typically occurs in young males; however, its clinical significance is unknown. Given the prevalence of the hypertension and its contribution to global morbidity and mortality, a synthesis of the most recent available evidence around isolated systolic hypertension is warranted. This review aims firstly to review the haemodynamic and physical characteristics indicative of cardiovascular risk in young males (aged 18 to 30 years) with isolated systolic hypertension, and secondly to synthesize the associated clinical management recommendations reported in the literature. Six databases were systematically searched for all relevant peer-reviewed literature examining isolated systolic hypertension in young males. Search results were screened and examined for validity, those that did not meet the inclusion criteria were removed. A total of 20 articles were appropriate for inclusion. Key factors indicative of cardiovascular risk in isolated systolic hypertension were characterized by several distinctive haemodynamic parameters and physical characteristics. After the literature was synthesized based around these key factors, two distinct cohorts (healthy and unhealthy) were highlighted. The healthy cohort of younger males with isolated systolic hypertension was associated with a decreased cardiovascular risk and therefore no medical interventions were recommended. The second (unhealthy) cohort was, however, associated with an increased cardiovascular risk and may therefore, benefit from antihypertensive therapy.
dc.description.peerreviewedYes
dc.languageeng
dc.publisherSpringer Science and Business Media LLC
dc.relation.ispartofpagefrom12
dc.relation.ispartofissue1
dc.relation.ispartofjournalClinical Hypertension
dc.relation.ispartofvolume27
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode3202
dc.subject.keywordsBlood pressure
dc.subject.keywordsCardiovascular diseases
dc.subject.keywordsHypertension
dc.subject.keywordsMale
dc.titleIsolated systolic hypertension in young males: a scoping review
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationScott, H; Barton, MJ; Johnston, ANB, Isolated systolic hypertension in young males: a scoping review, Clinical Hypertension, 2021, 27 (1), pp. 12-
dcterms.dateAccepted2021-05-21
dcterms.licensehttps://creativecommons.org/licenses/by/4.0/
dc.date.updated2021-06-22T04:10:09Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© The Author(s). 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.
gro.hasfulltextFull Text
gro.griffith.authorBarton, Matthew J.
gro.griffith.authorJohnston, Amy N.


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