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  • The use of extracorporeal membrane oxygenation in children with acute fulminant myocarditis

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    Fraser497876-Published.pdf (1.568Mb)
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    Version of Record (VoR)
    Author(s)
    Heinsar, S
    Raman, S
    Suen, JY
    Cho, HJ
    Fraser, JF
    Griffith University Author(s)
    Fraser, John F.
    Year published
    2021
    Metadata
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    Abstract
    Acute fulminant myocarditis (AFM) occurs as an inflammatory response to an initial myocardial insult. Its rapid and deadly progression calls for prompt diagnosis with aggressive treatment measures. The demonstration of its excellent recovery potential has led to increasing use of mechanical circulatory support, especially extracorporeal membrane oxygenation (ECMO). Arrhythmias, organ failure, elevated cardiac biomarkers, and decreased ventricular function at presentation predict re-quire ment for ECMO. In these patients, ECMO should be considered earlier as the clinical course of AFM can be unpre-dictable and can lead to ...
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    Acute fulminant myocarditis (AFM) occurs as an inflammatory response to an initial myocardial insult. Its rapid and deadly progression calls for prompt diagnosis with aggressive treatment measures. The demonstration of its excellent recovery potential has led to increasing use of mechanical circulatory support, especially extracorporeal membrane oxygenation (ECMO). Arrhythmias, organ failure, elevated cardiac biomarkers, and decreased ventricular function at presentation predict re-quire ment for ECMO. In these patients, ECMO should be considered earlier as the clinical course of AFM can be unpre-dictable and can lead to rapid haemodynamic collapse. Key uncertainties that clinicians face when managing children with AFM such as timing of initiation of ECMO and left ventricular decompression need further investigation.
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    Journal Title
    Clinical and Experimental Pediatrics
    Volume
    64
    Issue
    5
    DOI
    https://doi.org/10.3345/CEP.2020.00836
    Copyright Statement
    © 2021 by The Korean Pediatric Society. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
    Subject
    Clinical sciences
    Publication URI
    http://hdl.handle.net/10072/405324
    Collection
    • Journal articles

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