The use of extracorporeal membrane oxygenation in children with acute fulminant myocarditis
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Author(s)
Heinsar, S
Raman, S
Suen, JY
Cho, HJ
Fraser, JF
Griffith University Author(s)
Year published
2021
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Show full item recordAbstract
Acute fulminant myocarditis (AFM) occurs as an inflammatory response to an initial myocardial insult. Its rapid and deadly progression calls for prompt diagnosis with aggressive treatment measures. The demonstration of its excellent recovery potential has led to increasing use of mechanical circulatory support, especially extracorporeal membrane oxygenation (ECMO). Arrhythmias, organ failure, elevated cardiac biomarkers, and decreased ventricular function at presentation predict re-quire ment for ECMO. In these patients, ECMO should be considered earlier as the clinical course of AFM can be unpre-dictable and can lead to ...
View more >Acute fulminant myocarditis (AFM) occurs as an inflammatory response to an initial myocardial insult. Its rapid and deadly progression calls for prompt diagnosis with aggressive treatment measures. The demonstration of its excellent recovery potential has led to increasing use of mechanical circulatory support, especially extracorporeal membrane oxygenation (ECMO). Arrhythmias, organ failure, elevated cardiac biomarkers, and decreased ventricular function at presentation predict re-quire ment for ECMO. In these patients, ECMO should be considered earlier as the clinical course of AFM can be unpre-dictable and can lead to rapid haemodynamic collapse. Key uncertainties that clinicians face when managing children with AFM such as timing of initiation of ECMO and left ventricular decompression need further investigation.
View less >
View more >Acute fulminant myocarditis (AFM) occurs as an inflammatory response to an initial myocardial insult. Its rapid and deadly progression calls for prompt diagnosis with aggressive treatment measures. The demonstration of its excellent recovery potential has led to increasing use of mechanical circulatory support, especially extracorporeal membrane oxygenation (ECMO). Arrhythmias, organ failure, elevated cardiac biomarkers, and decreased ventricular function at presentation predict re-quire ment for ECMO. In these patients, ECMO should be considered earlier as the clinical course of AFM can be unpre-dictable and can lead to rapid haemodynamic collapse. Key uncertainties that clinicians face when managing children with AFM such as timing of initiation of ECMO and left ventricular decompression need further investigation.
View less >
Journal Title
Clinical and Experimental Pediatrics
Volume
64
Issue
5
Copyright Statement
© 2021 by The Korean Pediatric Society. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Subject
Clinical sciences