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  • Group for Research and Assessment of Psoriasis and Psoriatic Arthritis 2015 treatment recommendations for psoriatic arthritis

    Author(s)
    Coates, Laura C
    Kavanaugh, Arthur
    Mease, Philip J
    Soriano, Enrique R
    Acosta-Felquer, Maria Laura
    Armstrong, April W
    Bautista-Molano, Wilson
    Bochncke, Wolf-Henning
    Campbc, Willemina
    Cauli, Alberto
    Espinoza, Luis R
    FitzGerald, Oliver
    Gladman, Dafna D
    Nash, Peter
    et al.
    Griffith University Author(s)
    Nash, Peter
    Year published
    2016
    Metadata
    Show full item record
    Abstract
    Objective: To update the 2009 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations for the spectrum of manifestations affecting patients with psoriatic arthritis (PsA). Methods: GRAPPA rheumatologists, dermatologists, and PsA patients drafted overarching principles for the management of PsA, based on consensus achieved at face-to-face meetings and via online surveys. We conducted literature reviews regarding treatment for the key domains of PsA (arthritis, spondylitis, enthesitis, dactylitis, skin disease, and nail disease) and convened a new group to identify pertinent ...
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    Objective: To update the 2009 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations for the spectrum of manifestations affecting patients with psoriatic arthritis (PsA). Methods: GRAPPA rheumatologists, dermatologists, and PsA patients drafted overarching principles for the management of PsA, based on consensus achieved at face-to-face meetings and via online surveys. We conducted literature reviews regarding treatment for the key domains of PsA (arthritis, spondylitis, enthesitis, dactylitis, skin disease, and nail disease) and convened a new group to identify pertinent comorbidities and their effect on treatment. Finally, we drafted treatment recommendations for each of the clinical manifestations and assessed the level of agreement for the overarching principles and treatment recommendations among GRAPPA members, using an online questionnaire. Results: Six overarching principles had ≥80% agreement among both health care professionals (n = 135) and patient research partners (n = 10). We developed treatment recommendations and a schema incorporating these principles for arthritis, spondylitis, enthesitis, dactylitis, skin disease, nail disease, and comorbidities in the setting of PsA, using the Grading of Recommendations, Assessment, Development and Evaluation process. Agreement of >80% was reached for approval of the individual recommendations and the overall schema. Conclusion: We present overarching principles and updated treatment recommendations for the key manifestations of PsA, including related comorbidities, based on a literature review and consensus of GRAPPA members (rheumatologists, dermatologists, other health care providers, and patient research partners). Further updates are anticipated as the therapeutic landscape in PsA evolves.
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    Journal Title
    Arthritis & Rheumatology
    Volume
    68
    Issue
    5
    DOI
    https://doi.org/10.1002/art.39573
    Subject
    Rheumatology and arthritis
    Science & Technology
    Life Sciences & Biomedicine
    Rheumatology
    ORAL PHOSPHODIESTERASE-4 INHIBITOR
    ANTI-INTERLEUKIN-17A MONOCLONAL-ANTIBODY
    Publication URI
    http://hdl.handle.net/10072/406386
    Collection
    • Journal articles

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