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dc.contributor.authorMehdipour, Ali
dc.contributor.authorYousefi-Ahmadipour, Aliakbar
dc.contributor.authorKennedy, Derek
dc.contributor.authorArababadi, Mohammad Kazemi
dc.date.accessioned2021-08-03T03:58:33Z
dc.date.available2021-08-03T03:58:33Z
dc.date.issued2021
dc.identifier.issn0198-8859
dc.identifier.doi10.1016/j.humimm.2021.03.008
dc.identifier.urihttp://hdl.handle.net/10072/406530
dc.description.abstractIonizing radiation, including X and gamma rays, are used for various purposes such as; medicine, nuclear power, research, manufacturing, food preservation and construction. Furthermore, people are also exposed to ionizing radiation from their workplace or the environment. Apart from DNA fragmentation resulting in apoptosis, several additional mechanisms have been proposed to describe how radiation can alter human cell functions. Ionizing radiation may alter immune responses, which are the main cause of human disorders. Toll like receptors (TLRs) are important human innate immunity receptors which participate in several immune and non-immune cell functions including, induction of appropriate immune responses and immune related disorders. Based on the role played by ionizing radiation on human cell systems, it has been hypothesized that radiation may affect immune responses. Therefore, the main aim of this review article is to discuss recent information regarding the effects of ionizing radiation on TLRs and their related disorders.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherElsevier
dc.relation.ispartofpagefrom446
dc.relation.ispartofpageto454
dc.relation.ispartofissue6
dc.relation.ispartofjournalHuman Immunology
dc.relation.ispartofvolume82
dc.subject.fieldofresearchImmunology
dc.subject.fieldofresearchcode3204
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsToll like receptors
dc.subject.keywordsIonizing radiation
dc.titleIonizing radiation and toll like receptors: A systematic review article
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationMehdipour, A; Yousefi-Ahmadipour, A; Kennedy, D; Arababadi, MK, Ionizing radiation and toll like receptors: A systematic review article, Human Immunology, 2021, 82 (6), pp. 446-454
dcterms.dateAccepted2021-03-19
dc.date.updated2021-08-03T03:55:47Z
gro.hasfulltextNo Full Text
gro.griffith.authorKennedy, Derek D.


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