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dc.contributor.authorZafar, Sobia
dc.contributor.authorSiddiqi, Allauddin
dc.date.accessioned2021-08-18T03:09:11Z
dc.date.available2021-08-18T03:09:11Z
dc.date.issued2020
dc.identifier.issn1343-4934
dc.identifier.doi10.2334/josnusd.20-0083
dc.identifier.urihttp://hdl.handle.net/10072/407038
dc.description.abstractA systematic review was conducted to identify the biological responses, allergic reaction, hypersensitivity, toxicity, and ion release profile associated with pediatric stainless steel crowns (SSCs) in the existing literature. A systematic search was undertaken according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. The inclusion criteria consisted of patients younger than 20 years of age with SSC placement on primary or permanent teeth and in vivo and in vitro exposure to SSCs. Outcomes measures included adverse oral/mucosal effects; removal/failure/replacement of the SSC; type of allergic reaction; nickel (Ni) or other ion levels in bodily fluids, cellular, genotoxic, cytotoxic, mutagenic or carcinogenic effects related to the SSC. After an initial search of 764 studies in the database, 17 articles were included in the analysis. Evidence of allergic reactions to SSCs in children is limited and obtained from mostly low-quality research. Some studies showed that the amount of Ni detected was less than the amount ingested in the daily diet. In contrast, other studies reported a significantly higher release of Ni occurred into the saliva in acidic environments. There is some concern about the leaching of metal ions such as Ni from SSCs in children at high risk for caries. Further long-term studies are required to investigate this phenomenon.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherNihon University
dc.relation.ispartofpagefrom245
dc.relation.ispartofpageto249
dc.relation.ispartofissue3
dc.relation.ispartofjournalJournal of Oral Science
dc.relation.ispartofvolume62
dc.subject.fieldofresearchDentistry
dc.subject.fieldofresearchcode3203
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsDentistry, Oral Surgery & Medicine
dc.subject.keywordsMaterials Science, Biomaterials
dc.titleBiological responses to pediatric stainless steel crowns
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationZafar, S; Siddiqi, A, Biological responses to pediatric stainless steel crowns, Journal of Oral Science, 2020, 62 (3), pp. 245-249
dc.date.updated2021-08-17T22:05:49Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2020 Nihon University School of Dentistry. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
gro.hasfulltextFull Text
gro.griffith.authorSiddiqi, Allauddin (Diny)


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