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dc.contributor.authorAnstey, SI
dc.contributor.authorKasimov, V
dc.contributor.authorJenkins, C
dc.contributor.authorLegione, A
dc.contributor.authorDevlin, J
dc.contributor.authorAmery-Gale, J
dc.contributor.authorGilkerson, J
dc.contributor.authorHair, S
dc.contributor.authorPerkins, N
dc.contributor.authorPeel, AJ
dc.contributor.authorBorel, N
dc.contributor.authorPannekoek, Y
dc.contributor.authorChaber, AL
dc.contributor.authorWoolford, L
dc.contributor.authorTimms, P
dc.contributor.authorJelocnik, M
dc.date.accessioned2021-08-30T01:53:32Z
dc.date.available2021-08-30T01:53:32Z
dc.date.issued2021
dc.identifier.issn2076-0817
dc.identifier.doi10.3390/pathogens10081015
dc.identifier.urihttp://hdl.handle.net/10072/407374
dc.description.abstractChlamydia psittaci is traditionally regarded as a globally distributed avian pathogen that can cause zoonotic spill-over. Molecular research has identified an extended global host range and significant genetic diversity. However, Australia has reported a reduced host range (avian, horse, and human) with a dominance of clonal strains, denoted ST24. To better understand the widespread of this strain type in Australia, multilocus sequence typing (MLST) and ompA genotyping were applied on samples from a range of hosts (avian, equine, marsupial, and bovine) from Australia. MLST confirms that clonal ST24 strains dominate infections of Australian psittacine and equine hosts (82/88; 93.18%). However, this study also found novel hosts (Australian white ibis, King parrots, racing pigeon, bovine, and a wallaby) and demonstrated that strain diversity does exist in Australia. The discovery of a C. psittaci novel strain (ST306) in a novel host, the Western brush wallaby, is the first detection in a marsupial. Analysis of the results of this study applied a multidisciplinary approach regarding Chlamydia infections, equine infectious disease, ecology, and One Health. Recommendations include an update for the descriptive framework of C. psittaci disease and cell biology work to inform pathogenicity and complement molecular epidemiology.
dc.description.peerreviewedYes
dc.languageen
dc.publisherMDPI AG
dc.relation.ispartofpagefrom1015
dc.relation.ispartofissue8
dc.relation.ispartofjournalPathogens
dc.relation.ispartofvolume10
dc.subject.fieldofresearchImmunology
dc.subject.fieldofresearchMedical microbiology
dc.subject.fieldofresearchcode3204
dc.subject.fieldofresearchcode3207
dc.titleChlamydia psittaci st24: Clonal strains of one health importance dominate in australian horse, bird and human infections
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationAnstey, SI; Kasimov, V; Jenkins, C; Legione, A; Devlin, J; Amery-Gale, J; Gilkerson, J; Hair, S; Perkins, N; Peel, AJ; Borel, N; Pannekoek, Y; Chaber, AL; Woolford, L; Timms, P; Jelocnik, M, Chlamydia psittaci st24: Clonal strains of one health importance dominate in australian horse, bird and human infections, Pathogens, 2021, 10 (8), pp. 1015
dcterms.licensehttps://creativecommons.org/licenses/by/4.0/
dc.date.updated2021-08-29T23:35:01Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorPeel, Alison J.


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