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dc.contributor.authorRamanathan, Kollengode
dc.contributor.authorMohammed, Hend
dc.contributor.authorHopkins, Peter
dc.contributor.authorCorley, Amanda
dc.contributor.authorCaruana, Lawrence
dc.contributor.authorDunster, Kimble
dc.contributor.authorBarnett, Adrian G
dc.contributor.authorFraser, John F
dc.date.accessioned2023-06-08T21:46:35Z
dc.date.available2023-06-08T21:46:35Z
dc.date.issued2016
dc.identifier.issn1198-2241en_US
dc.identifier.doi10.1155/2016/2471207en_US
dc.identifier.urihttp://hdl.handle.net/10072/407678
dc.description.abstractBackground: Lung transplantation is the optimal treatment for end stage lung disease. Donor shortage necessitates single-lung transplants (SLT), yet minimal data exists regarding regional ventilation in diseased versus transplanted lung measured by Electrical Impedance Tomography (EIT). Method: We aimed to determine regional ventilation in six SLT outpatients using EIT. We assessed end expiratory volume and tidal volumes. End expiratory lung impedance (EELI) and Global Tidal Variation of Impedance were assessed in supine, right lateral, left lateral, sitting, and standing positions in transplanted and diseased lungs. A mixed model with random intercept per subject was used for statistical analysis. Results: EELI was significantly altered between diseased and transplanted lungs whilst lying on right and left side. One patient demonstrated pendelluft between lungs and was therefore excluded for further comparison of tidal variation. Tidal variation was significantly higher in the transplanted lung for the remaining five patients in all positions, except when lying on the right side. Conclusion: Ventilation to transplanted lung is better than diseased lung, especially in lateral positions. Positioning in patients with active unilateral lung pathologies will be implicated. This is the first study demonstrating changes in regional ventilation, associated with changes of position between transplanted and diseased lung.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherHindawi Limiteden_US
dc.relation.ispartofpagefrom2471207en_US
dc.relation.ispartofjournalCanadian Respiratory Journalen_US
dc.relation.ispartofvolume2016en_US
dc.subject.fieldofresearchRespiratory diseasesen_US
dc.subject.fieldofresearchBiomedical and clinical sciencesen_US
dc.subject.fieldofresearchcode320103en_US
dc.subject.fieldofresearchcode32en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsLife Sciences & Biomedicineen_US
dc.subject.keywordsRespiratory Systemen_US
dc.subject.keywordsAIRen_US
dc.titleSingle-lung transplant results in position dependent changes in regional ventilation: An observational case series using electrical impedance tomographyen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationRamanathan, K; Mohammed, H; Hopkins, P; Corley, A; Caruana, L; Dunster, K; Barnett, AG; Fraser, JF, Single-lung transplant results in position dependent changes in regional ventilation: An observational case series using electrical impedance tomography, Canadian Respiratory Journal, 2016, 2016, pp. 2471207en_US
dcterms.dateAccepted2016-06-09
dcterms.licensehttps://creativecommons.org/licenses/by/4.0/en_US
dc.date.updated2021-09-06T06:30:19Z
dc.description.versionVersion of Record (VoR)en_US
gro.rights.copyright© 2016 Kollengode Ramanathan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
gro.hasfulltextFull Text
gro.griffith.authorCorley, Amanda


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