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dc.contributor.authorDiaz, Abbey
dc.contributor.authorKang, Jimin
dc.contributor.authorMoore, Suzanne P
dc.contributor.authorBaade, Peter
dc.contributor.authorLangbecker, Danette
dc.contributor.authorCondon, John R
dc.contributor.authorValery, Patricia C
dc.description.abstractBackground: Comorbidity is associated with poor outcomes for cancer patients but it is less clear how it influences cancer prevention and early detection. This review synthesizes evidence from studies that have quantified the association between comorbidity and participation in breast and cervical screening. Methods: PubMed, CINAHL and EMBASE databases were systematically searched using key terms related to cancer screening and comorbidity for original research articles published between 1 January 1991 and 21 March 2016. Two reviewers independently screened 1283 studies that met eligibility criteria related to Population (adult, non-cancer populations), Exposure (comorbidity), Comparison (a ‘no comorbidity’ group), and Outcome (participation in breast cancer or cervical screening). Data was extracted and risk of bias assessed using a standardised tool from the 22 studies identified for inclusion (17 breast; 13 cervical). Meta-analyses were performed for participation in breast and cervical screening, stratified by important study characteristics. Results: The majority of studies were conducted in the United States. Results of individual studies were variable. Most had medium to high risk of bias. Based on the three “low risk of bias” studies, mammography screening was less common among those with comorbidity (pooled Odds Ratio 0.66, 95%CI 0.44–0.88). The one “low risk of bias” study of cervical screening reported a negative association between comorbidity and participation. Conclusion: While a definitive conclusion could not be drawn, the results from high quality studies suggest that women with comorbidity are less likely to participate in breast, and possibly cervical, cancer screening.
dc.relation.ispartofjournalCancer Epidemiology
dc.subject.fieldofresearchOncology and carcinogenesis
dc.subject.fieldofresearchHealth services and systems
dc.subject.fieldofresearchPublic health
dc.subject.keywordsScience & Technology
dc.subject.keywordsLife Sciences & Biomedicine
dc.subject.keywordsPublic, Environmental & Occupational Health
dc.titleAssociation between comorbidity and participation in breast and cervical cancer screening: A systematic review and meta-analysis
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationDiaz, A; Kang, J; Moore, SP; Baade, P; Langbecker, D; Condon, JR; Valery, PC, Association between comorbidity and participation in breast and cervical cancer screening: A systematic review and meta-analysis, Cancer Epidemiology, 2017, 47, pp. 7-19
gro.hasfulltextNo Full Text
gro.griffith.authorBaade, Peter D.

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