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  • The development of malaria diagnostic techniques: a review of the approaches with focus on dielectrophoretic and magnetophoretic methods

    Author(s)
    Kasetsirikul, Surasak
    Buranapong, Jirayut
    Srituravanich, Werayut
    Kaewthamasorn, Morakot
    Pimpin, Alongkorn
    Griffith University Author(s)
    Kasetsirikul, Surasak
    Year published
    2016
    Metadata
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    Abstract
    The large number of deaths caused by malaria each year has increased interest in the development of effective malaria diagnoses. At the early-stage of infection, patients show non-specific symptoms or are asymptomatic, which makes it difficult for clinical diagnosis, especially in non-endemic areas. Alternative diagnostic methods that are timely and effective are required to identify infections, particularly in field settings. This article reviews conventional malaria diagnostic methods together with recently developed techniques for both malaria detection and infected erythrocyte separation. Although many alternative ...
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    The large number of deaths caused by malaria each year has increased interest in the development of effective malaria diagnoses. At the early-stage of infection, patients show non-specific symptoms or are asymptomatic, which makes it difficult for clinical diagnosis, especially in non-endemic areas. Alternative diagnostic methods that are timely and effective are required to identify infections, particularly in field settings. This article reviews conventional malaria diagnostic methods together with recently developed techniques for both malaria detection and infected erythrocyte separation. Although many alternative techniques have recently been proposed and studied, dielectrophoretic and magnetophoretic approaches are among the promising new techniques due to their high specificity for malaria parasite-infected red blood cells. The two approaches are discussed in detail, including their principles, types, applications and limitations. In addition, other recently developed techniques, such as cell deformability and morphology, are also overviewed in this article.
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    Journal Title
    Malaria Journal
    Volume
    15
    Issue
    1
    DOI
    https://doi.org/10.1186/s12936-016-1400-9
    Subject
    Microbiology
    Medical microbiology
    Health services and systems
    Public health
    Science & Technology
    Life Sciences & Biomedicine
    Infectious Diseases
    Parasitology
    Tropical Medicine
    Publication URI
    http://hdl.handle.net/10072/407775
    Collection
    • Journal articles

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