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dc.contributor.authorTa, Hang T
dc.contributor.authorLi, Zhen
dc.contributor.authorWu, Yuao
dc.contributor.authorCowin, Gary
dc.contributor.authorZhang, Shaohua
dc.contributor.authorYago, Anya
dc.contributor.authorWhittaker, Andrew K
dc.contributor.authorXu, Zhi Ping
dc.description.abstractThis study aims to compare the relaxivities of ultra-small dual positive and negative contrast iron oxide nanoparticles (DCION) at different magnetic field strengths ranging from 4.7 to 16.4 T at physiological temperatures; and to investigate the effect of particle aggregation on relaxivities. Relaxivities of DCIONs were determined by magnetic resonance imaging scanners at 4.7, 7, 9.4, and 16.4 T. Both longitudinal (T 1) and transverse relaxation times (T 2) were measured by appropriate spin-echo sequences. It has been found that both longitudinal and transverse relaxivities are significantly dependent on the magnetic field strength. Particle aggregation also strongly affects the relaxivities. Awareness of the field strength and particle colloid stability is crucial for the comparison and evaluation of relaxivity values of these ultra-small iron oxide nanoparticles, and also for their medical applications as contrast agents.
dc.relation.ispartofjournalMaterials Research Express
dc.subject.fieldofresearchMaterials engineering
dc.subject.keywordsScience & Technology
dc.subject.keywordsMaterials Science, Multidisciplinary
dc.subject.keywordsMaterials Science
dc.subject.keywordsdual contrast iron oxide nanoparticle
dc.titleEffects of magnetic field strength and particle aggregation on relaxivity of ultra-small dual contrast iron oxide nanoparticles
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationTa, HT; Li, Z; Wu, Y; Cowin, G; Zhang, S; Yago, A; Whittaker, AK; Xu, ZP, Effects of magnetic field strength and particle aggregation on relaxivity of ultra-small dual contrast iron oxide nanoparticles, Materials Research Express, 2017, 4 (11)
gro.hasfulltextNo Full Text
gro.griffith.authorTa, Hang
gro.griffith.authorWu, Yuao

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