Chronic rhinosinusitis: a microbiome in dysbiosis and the search for alternative treatment options
Author(s)
Bordin, Amanda
Sidjabat, Hanna E
Cottrell, Kyra
Cervin, Anders
Griffith University Author(s)
Year published
2016
Metadata
Show full item recordAbstract
Chronic rhinosinusitis (CRS) is a common chronic disease. While CRS is a multifactorial disease, many cases involve an imbalance in the sinus bacterial microbiome. This article reviews the composition of the healthy human sinus microbiome compared to the microbiome of CRS patients. Issues with current treatment options, particularly antibiotics, are discussed. Insights into the future of CRS treatment are also explored, principally with regards to probiotics.Chronic rhinosinusitis (CRS) is a common chronic disease. While CRS is a multifactorial disease, many cases involve an imbalance in the sinus bacterial microbiome. This article reviews the composition of the healthy human sinus microbiome compared to the microbiome of CRS patients. Issues with current treatment options, particularly antibiotics, are discussed. Insights into the future of CRS treatment are also explored, principally with regards to probiotics.
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Journal Title
Microbiology Australia
Volume
37
Issue
3
Subject
Biochemistry and cell biology
Microbiology
Science & Technology
Life Sciences & Biomedicine
Microbiology
Staphylococcus-Aureus
Diversity