Show simple item record

dc.contributor.authorSuetani, S
dc.contributor.authorHonarparvar, F
dc.contributor.authorSiskind, D
dc.contributor.authorHindley, G
dc.contributor.authorVeronese, N
dc.contributor.authorVancampfort, D
dc.contributor.authorAllen, L
dc.contributor.authorSolmi, M
dc.contributor.authorLally, J
dc.contributor.authorGaughran, F
dc.contributor.authorStubbs, B
dc.contributor.authorPillinger, T
dc.date.accessioned2021-09-27T02:13:12Z
dc.date.available2021-09-27T02:13:12Z
dc.date.issued2021
dc.identifier.issn0920-9964
dc.identifier.doi10.1016/j.schres.2021.08.022
dc.identifier.urihttp://hdl.handle.net/10072/408383
dc.description.abstractIntroduction: Despite respiratory disease being a major cause of excess mortality in people with schizophrenia, the prevalence of respiratory conditions in this population is poorly defined. A systematic review and meta-analysis were conducted to establish the prevalence and association of respiratory diseases in people with schizophrenia. Material and methods: Major electronic databases were searched from inception to 27 April 2020 for articles reporting respiratory disease (asthma, chronic obstructive pulmonary disease [COPD], pneumonia, and tuberculosis) in people with schizophrenia and, where possible, a control group. A random-effects meta-analysis was conducted. The study was registered with PROSPERO (CRD42018115137). Results: Of 1569 citations, 21 studies consisting of 619,214 individuals with schizophrenia and 52,159,551 controls were included in the meta-analysis. Compared to the general population, people with schizophrenia had significantly higher rates of COPD (odds ratio [OR]: 1.82, 95% CI: 1.28–2.57), asthma (OR: 1.70, 95% CI: 1.02–2.83), and pneumonia (OR: 2.62, 95% CI: 1.10–6.23). In people with schizophrenia, the prevalence of COPD was 7.7% (95% CI: 4.0–14.4), asthma 7.5% (95% CI: 4.9–11.3), pneumonia 10.3% (95% CI 5.4–18.6), and tuberculosis 0.3% (95% CI 0.1 –0.8). After adjusting for publication bias, the prevalence of COPD increased to 19.9% (95% CI: 9.6–36.7). Discussion: All respiratory diseases examined were significantly more prevalent in people with schizophrenia compared with the general population. Future studies should focus on improving the prevention and management of respiratory disease in this group to reduce associated excess mortality.
dc.description.peerreviewedYes
dc.languageeng
dc.publisherElsevier BV
dc.relation.ispartofpagefrom131
dc.relation.ispartofpageto140
dc.relation.ispartofjournalSchizophrenia Research
dc.relation.ispartofvolume237
dc.subject.fieldofresearchApplied and developmental psychology
dc.subject.fieldofresearchPsychiatry (incl. psychotherapy)
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchRespiratory diseases
dc.subject.fieldofresearchHealth sciences
dc.subject.fieldofresearchcode5201
dc.subject.fieldofresearchcode320221
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode320103
dc.subject.fieldofresearchcode42
dc.subject.keywordsAsthma
dc.subject.keywordsChronic obstructive pulmonary disease
dc.subject.keywordsLung disease
dc.subject.keywordsRespiratory disease
dc.subject.keywordsSchizophrenia
dc.titleIncreased rates of respiratory disease in schizophrenia: A systematic review and meta-analysis including 619,214 individuals with schizophrenia and 52,159,551 controls
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationSuetani, S; Honarparvar, F; Siskind, D; Hindley, G; Veronese, N; Vancampfort, D; Allen, L; Solmi, M; Lally, J; Gaughran, F; Stubbs, B; Pillinger, T, Increased rates of respiratory disease in schizophrenia: A systematic review and meta-analysis including 619,214 individuals with schizophrenia and 52,159,551 controls, Schizophrenia Research, 2021, 237, pp. 131-140
dcterms.dateAccepted2021-08-22
dc.date.updated2021-09-27T02:12:12Z
gro.hasfulltextNo Full Text
gro.griffith.authorSuetani, Shuichi


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record