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dc.contributor.authorKeogh, Justin WL
dc.contributor.authorGrigg, Josephine
dc.contributor.authorVertullo, Christopher J
dc.date.accessioned2023-06-13T04:21:33Z
dc.date.available2023-06-13T04:21:33Z
dc.date.issued2017
dc.identifier.issn2325-9671en_US
dc.identifier.doi10.1177/2325967117694334en_US
dc.identifier.urihttp://hdl.handle.net/10072/408868
dc.description.abstractBackground: Osteoarthritis (OA) is a degenerative joint disease affecting the knee joint of many middle-aged and older adults. As OA symptoms typically involve knee pain and stiffness, individuals with knee OA are often insufficiently physically active, have low levels of physical function, and are at increased risk of other comorbidities and reduced quality of life. While moderate-intensity continuous training (MICT) cycling is often recommended, little is known about the feasibility, safety, and benefits of high-intensity interval training (HIIT) cycling for this population, even though the feasibility, safety, and benefits of HIIT have been demonstrated in other chronic disease groups. Purpose: The primary objective of this pilot study was to examine the feasibility and safety of home-based HIIT and MICT cycling in middle-aged and older adults with knee OA. A secondary objective was to gain some insight into the relative efficacy of HIIT and MICT for improving health status (pain, stiffness, and disability), muscle function, and body composition in this population. This study protocol is being published separately to allow a detailed description of the research methods, explain the rationale for choosing the methodological details, and to stimulate consideration of the best means to simulate a research protocol that is relevant to a real-life treatment environment. Study Design: Randomized pilot study protocol. Methods: This trial sought to recruit 40 middle-aged and older adults with knee OA. Participants were randomly allocated to either continuous (MICT) or HIIT home-based cycle training programs, with both programs requiring the performance of 4 cycling sessions (approximately 25 minutes per session) each week. Participants weremeasured at baseline and postintervention (8 weeks). Feasibility and safetywere assessed by adherence rate, dropout rate, and number of adverse events. The relative efficacy of the cycling programs was investigated by 2 knee OA health status questionnaires (Western Ontario and McMaster Universities Osteoarthritis Index scale [WOMAC] and the Lequesne Index) as well as the timed up and go, sit to stand, preferred gait speed, and body composition. Discussion: This pilot study appears to be the first study assessing the feasibility and safety of a home-based HIIT training program for middle-aged and older adults with knee OA. As HIIT has been demonstrated to be more effective than MICT for improving aspects of health status, body composition, and/or muscular function in other chronic disease groups, the current study has the potential to improve patient outcomes and inform the design of future randomized controlled trials.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherSAGE PUBLICATIONS INCen_US
dc.relation.ispartofissue3en_US
dc.relation.ispartofjournalThe Orthopaedic Journal of Sports Medicineen_US
dc.relation.ispartofvolume5en_US
dc.subject.fieldofresearchClinical sciencesen_US
dc.subject.fieldofresearchSports science and exerciseen_US
dc.subject.fieldofresearchcode3202en_US
dc.subject.fieldofresearchcode4207en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsLife Sciences & Biomedicineen_US
dc.subject.keywordsOrthopedicsen_US
dc.subject.keywordsSport Sciencesen_US
dc.subject.keywordsarthritisen_US
dc.titleIs Home-Based, High-Intensity Interval Training Cycling Feasible and Safe for Patients With Knee Osteoarthritis?: Study Protocol for a Randomized Pilot Studyen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationKeogh, JWL; Grigg, J; Vertullo, CJ, Is Home-Based, High-Intensity Interval Training Cycling Feasible and Safe for Patients With Knee Osteoarthritis?: Study Protocol for a Randomized Pilot Study, The Orthopaedic Journal of Sports Medicine, 2017, 5 (3)en_US
dcterms.licensehttp://www.creativecommons.org/licenses/by-nc-nd/3.0/en_US
dc.date.updated2021-10-12T01:50:53Z
dc.description.versionVersion of Record (VoR)en_US
gro.rights.copyright© The Author(s) 2017. This open-access article is published and distributed under the Creative Commons Attribution - NonCommercial - No Derivatives License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits the noncommercial use, distribution, and reproduction of the article in any medium, provided the original author and source are credited. You may not alter, transform, or build upon this article without the permission of the Author(s). For reprints and permission queries, please visit SAGE’s website at http://www.sagepub.com/journalsPermissions.nav.en_US
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gro.griffith.authorVertullo, Christopher J.


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