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dc.contributor.authorNawaz, Ali
dc.contributor.authorLiu, Qian
dc.contributor.authorLeong, Wei Lin
dc.contributor.authorFairfull-Smith, Kathryn E
dc.contributor.authorSonar, Prashant
dc.date.accessioned2021-10-12T04:19:46Z
dc.date.available2021-10-12T04:19:46Z
dc.date.issued2021
dc.identifier.issn0935-9648
dc.identifier.doi10.1002/adma.202101874
dc.identifier.urihttp://hdl.handle.net/10072/408913
dc.description.abstractOrganic electrochemical transistors (OECTs) are presently a focus of intense research and hold great potential in expanding the horizons of the bioelectronics industry. The notable characteristics of OECTs, including their electrolyte-gating, which offers intimate interfacing with biological environments, and aqueous stability, make them particularly suitable to be operated within a living organism (in vivo). Unlike the existing in vivo bioelectronic devices, mostly based on rigid metal electrodes, OECTs form a soft mechanical contact with the biological milieu and ensure a high signal-to-noise ratio because of their powerful amplification capability. Such features make OECTs particularly desirable for a wide range of in vivo applications, including electrophysiological recordings, neuron stimulation, and neurotransmitter detection, and regulation of plant processes in vivo. In this review, a systematic compilation of the in vivo applications is presented that are addressed by the OECT technology. First, the operating mechanisms, and the device design and materials design principles of OECTs are examined, and then multiple examples are provided from the literature while identifying the unique device properties that enable the application progress. Finally, one critically looks at the future of the OECT technology for in vivo bioelectronic applications.
dc.description.peerreviewedYes
dc.languageeng
dc.publisherWiley
dc.relation.ispartofpagefrome2101874
dc.relation.ispartofjournalAdvanced Materials
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchPhysical sciences
dc.subject.fieldofresearchChemical sciences
dc.subject.fieldofresearchEngineering
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode51
dc.subject.fieldofresearchcode34
dc.subject.fieldofresearchcode40
dc.subject.keywordsOECTs
dc.subject.keywordselectrophysiology
dc.subject.keywordsin vivo bioelectronics
dc.subject.keywordsneural interfacing
dc.subject.keywordsorganic transistors
dc.titleOrganic Electrochemical Transistors for In Vivo Bioelectronics
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationNawaz, A; Liu, Q; Leong, WL; Fairfull-Smith, KE; Sonar, P, Organic Electrochemical Transistors for In Vivo Bioelectronics, Advanced Materials, 2021, pp. e2101874
dc.date.updated2021-10-10T22:05:05Z
gro.description.notepublicThis publication has been entered in Griffith Research Online as an advanced online version.
gro.hasfulltextNo Full Text
gro.griffith.authorSonar, Prashant


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