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  • Prevalence of diabetes in people with intellectual disabilities and age- and gender-matched controls: A meta-analysis

    Author(s)
    Vancampfort, Davy
    Schuch, Felipe
    Van Damme, Tine
    Firth, Joseph
    Suetani, Shuichi
    Stubbs, Brendon
    Van Biesen, Debbie
    Griffith University Author(s)
    Suetani, Shuichi
    Year published
    2021
    Metadata
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    Abstract
    BACKGROUND: This meta-analysis aims to: (i) describe the pooled prevalence of diabetes in people with intellectual disabilities, (ii) investigate the association with demographic, clinical and treatment-related factors and (iii) compare the prevalence versus age- and gender-matched general population controls. METHODS: Pubmed, Embase and CINAHL were searched until 01 May 2021. Random effects meta-analysis and an odds ratio analysis were conducted to compare rates with controls. RESULTS: The trim- and fill-adjusted pooled diabetes prevalence amongst 55,548 individuals with intellectual disabilities (N studies = 33) was 8.5% ...
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    BACKGROUND: This meta-analysis aims to: (i) describe the pooled prevalence of diabetes in people with intellectual disabilities, (ii) investigate the association with demographic, clinical and treatment-related factors and (iii) compare the prevalence versus age- and gender-matched general population controls. METHODS: Pubmed, Embase and CINAHL were searched until 01 May 2021. Random effects meta-analysis and an odds ratio analysis were conducted to compare rates with controls. RESULTS: The trim- and fill-adjusted pooled diabetes prevalence amongst 55,548 individuals with intellectual disabilities (N studies = 33) was 8.5% (95% CI = 7.2%-10.0%). The trim- and fill-adjusted odds for diabetes was 2.46 times higher (95% CI = 1.89-3.21) (n = 42,684) versus controls (n = 4,177,550). Older age (R2  = .83, p < .001), smoking (R2  = .30, p = .009) and co-morbid depression (R2  = .18, p = .04), anxiety (R2  = .97, p < .001), and hypertension (R2  = 0.29, p < .001) were associated with higher diabetes prevalence rates. CONCLUSIONS: Our findings demonstrate that people with intellectual disabilities are at an increased risk of diabetes, and therefore routine screening and multidisciplinary management of diabetes is needed.
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    Journal Title
    Journal of Applied Research in Intellectual Disabilities
    DOI
    https://doi.org/10.1111/jar.12949
    Note
    This publication has been entered in Griffith Research Online as an advanced online version.
    Subject
    Social work
    Psychology
    Cognitive neuroscience
    Public health
    anxiety
    depression
    hyperglycaemia
    hypertension
    intellectual disability
    Publication URI
    http://hdl.handle.net/10072/409428
    Collection
    • Journal articles

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