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  • Impacts of peritoneal cancer index on the survival outcomes of patients with colorectal peritoneal carcinomatosis

    Author(s)
    Huang, Y
    Alzahrani, NA
    Chua, TC
    Liauw, W
    Morris, DL
    Griffith University Author(s)
    Chua, Terence
    Year published
    2016
    Metadata
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    Abstract
    Introduction: Peritoneal cancer index (PCI) has been suggested to be the most important prognostic factors for the outcomes in colorectal peritoneal carcinomatosis (CRPC). Methods: This was a retrospective study of prospectively collected data of 168 consecutive patients with CRPC following cytoreductive surgery (CRS) and perioperative intraperitoneal chemotherapy (PIC). Patients were divided into five groups according to their PCI. Results: Hospital mortality was 0%. Patients in low PCI groups had a significantly lower major morbidity rate, shorter intensive care unit and high dependency unit stay and higher overall survival ...
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    Introduction: Peritoneal cancer index (PCI) has been suggested to be the most important prognostic factors for the outcomes in colorectal peritoneal carcinomatosis (CRPC). Methods: This was a retrospective study of prospectively collected data of 168 consecutive patients with CRPC following cytoreductive surgery (CRS) and perioperative intraperitoneal chemotherapy (PIC). Patients were divided into five groups according to their PCI. Results: Hospital mortality was 0%. Patients in low PCI groups had a significantly lower major morbidity rate, shorter intensive care unit and high dependency unit stay and higher overall survival (p=0.017, 0.001, 0.046, p<0.001 respectively). Conclusion: Combined CRS with PIC can be safely performed to provide encouraging survival benefits for patients with CRPC. Our findings suggest that this approach is particularly beneficial for patients with low volume of disease. Early referral to specialist centre for evaluation is warranted for better survival outcomes.
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    Journal Title
    International Journal of Surgery
    Volume
    32
    DOI
    https://doi.org/10.1016/j.ijsu.2016.06.033
    Subject
    Clinical sciences
    Colorectal peritoneal carcinomatosis
    Peritoneal cancer index
    Relationship
    Survival outcomes
    Publication URI
    http://hdl.handle.net/10072/409993
    Collection
    • Journal articles

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