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dc.contributor.authorIrani, S
dc.date.accessioned2021-11-11T01:40:30Z
dc.date.available2021-11-11T01:40:30Z
dc.date.issued2016
dc.identifier.issn1735-5303en_US
dc.identifier.urihttp://hdl.handle.net/10072/410032
dc.description.abstractMany types of cancers develop in the oral and maxillofacial region. Squamous cell carcinoma is the most common cancer and constitutes over 90 percent of these tumors. Malignant transformation is a genetic process, which later makes a phenotyping change at the cellular level. Some cancers such as oral squamous cell carcinomas (OSCCs) develop from pre-malignant lesions and conditions. Despite advances in the treatment of OSCC, the 5-year survival rate remains approximately 50% due to inability of early detection of OSCC and precursor lesions. Early detection of oral cancer, especially in the premalignant stage, can decrease mortality and morbidity significantly. This article reviews some clinical, histopathological features and etiopathogenesis of pre-cancerous lesions of the oral cavity and skin of face and lip vermilion. A relevant English literature search in Pubmed, Science Direct, and Google Scholar was performed from 1930 to 2015. Full text of 191 articles met the specific inclusion criteria for this review.en_US
dc.description.peerreviewedYesen_US
dc.languageengen_US
dc.publisherIranian Society of Pathologyen_US
dc.publisher.urihttp://ijp.iranpath.org/article_21852.htmlen_US
dc.relation.ispartofpagefrom303en_US
dc.relation.ispartofpageto322en_US
dc.relation.ispartofissue4en_US
dc.relation.ispartofjournalIranian Journal of Pathologyen_US
dc.relation.ispartofvolume11en_US
dc.subject.fieldofresearchBiomedical and clinical sciencesen_US
dc.subject.fieldofresearchcode32en_US
dc.subject.keywordsFaceen_US
dc.subject.keywordsHeaden_US
dc.subject.keywordsLeukoplakiaen_US
dc.subject.keywordsMouthen_US
dc.subject.keywordsNeoplasmen_US
dc.titlePre-cancerous lesions in the oral and maxillofacial region: A literature review with special focus on etiopathogenesisen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationIrani, S, Pre-cancerous lesions in the oral and maxillofacial region: A literature review with special focus on etiopathogenesis, Iranian Journal of Pathology, 2016, 11 (4), pp. 303-322en_US
dc.date.updated2021-11-11T01:38:31Z
gro.hasfulltextNo Full Text
gro.griffith.authorIrani, Soussan


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