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dc.contributor.authorElgamoudi, Bassam A
dc.contributor.authorKorolik, Victoria
dc.date.accessioned2021-11-18T00:59:45Z
dc.date.available2021-11-18T00:59:45Z
dc.date.issued2021
dc.identifier.issn1422-0067
dc.identifier.doi10.3390/ijms222212159
dc.identifier.urihttp://hdl.handle.net/10072/410197
dc.description.abstractMicrobial biofilms occur naturally in many environmental niches and can be a significant reservoir of infectious microbes in zoonotically transmitted diseases such as that caused by Campylobacter jejuni, the leading cause of acute human bacterial gastroenteritis world-wide. The greatest challenge in reducing the disease caused by this organism is reducing transmission of C. jejuni to humans from poultry via the food chain. Biofilms enhance the stress tolerance and antimicrobial resistance of the microorganisms they harbor and are considered to play a crucial role for Campylobacter spp. survival and transmission to humans. Unconventional approaches to control biofilms and to improve the efficacy of currently used antibiotics are urgently needed. This review summarizes the use plant- and microorganism-derived antimicrobial and antibiofilm compounds such as essential oils, antimicrobial peptides (AMPs), polyphenolic extracts, algae extracts, probiotic-derived factors, d-amino acids (DAs) and glycolipid biosurfactants with potential to control biofilms formed by Campylobacter, and the suggested mechanisms of their action. Further investigation and use of such natural compounds could improve preventative and remedial strategies aimed to limit the transmission of campylobacters and other human pathogens via the food chain.
dc.description.peerreviewedYes
dc.languageen
dc.publisherMDPI AG
dc.relation.ispartofpagefrom12159
dc.relation.ispartofissue22
dc.relation.ispartofjournalInternational Journal of Molecular Sciences
dc.relation.ispartofvolume22
dc.subject.fieldofresearchGlycobiology
dc.subject.fieldofresearchcode310107
dc.titleCampylobacter Biofilms: Potential of Natural Compounds to Disrupt Campylobacter jejuni Transmission
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationElgamoudi, BA; Korolik, V, Campylobacter Biofilms: Potential of Natural Compounds to Disrupt Campylobacter jejuni Transmission, International Journal of Molecular Sciences, 22 (22), pp. 12159
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.date.updated2021-11-16T00:50:33Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorElgamoudi, Bassam A.
gro.griffith.authorKorolik, Victoria


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