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dc.contributor.authorCock, Ian
dc.contributor.editorIan Cock
dc.date.accessioned2017-05-03T11:29:06Z
dc.date.available2017-05-03T11:29:06Z
dc.date.issued2011
dc.date.modified2011-09-28T06:50:44Z
dc.identifier.issn22490167
dc.identifier.doi10.5530/pc.2011.1.3
dc.identifier.urihttp://hdl.handle.net/10072/41023
dc.description.abstractAloe vera has a long history of medicinal usage and its therapeutic properties have been well documented in a variety of bioassays. However, isolated Aloe vera leaf components generally do not display the same bioactivities, or have lower efficacies than crude juice/extracts. It is likely that several components work in a synergistic manner in the crude mixture, resulting in increased bioactivities. Furthermore, different laboratories often report varying bioactivities using the same extraction procedure on plant material from the same species. Individual Aloe vera cultivars may have widely varying levels of the bioactive phytochemicals. Due to the structure and chemical nature of many of the Aloe vera phytochemicals, it is likely that many of its reported medicinal properties are due to anti-oxidant or pro-oxidant effects. The anti-oxidant/pro-oxidant activities of many of Aloe vera's phytochemicals is dependent not only on their individual levels, but also on the ratios of various components, and on their individual redox states. Therefore, discrepencies between bioactivity studies are likely when using different crude mixtures. The potential differences between these crude mixtures need to be taken into account when analysing the reproducibility and efficacy of bioassays of crude extracts.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent896266 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherPharmacognosy Network Worldwide
dc.publisher.placeIndia
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom52
dc.relation.ispartofpageto62
dc.relation.ispartofissue1
dc.relation.ispartofjournalPharmacognosy Communications
dc.relation.ispartofvolume1
dc.rights.retentionY
dc.subject.fieldofresearchBiological Sciences not elsewhere classified
dc.subject.fieldofresearchPlant Biology
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciences
dc.subject.fieldofresearchcode069999
dc.subject.fieldofresearchcode0607
dc.subject.fieldofresearchcode1115
dc.titleProblems of Reproducibility and Efficacy of Bioassays Using Crude Extracts, with reference to Aloe vera
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Sciences, School of Natural Sciences
gro.rights.copyright© 2011 Phcog.net. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
gro.date.issued2011
gro.hasfulltextFull Text
gro.griffith.authorCock, Ian E.


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