dc.contributor.author | Fortier, Emmanuel | |
dc.contributor.author | Alavi, Maryam | |
dc.contributor.author | Bruneau, Julie | |
dc.contributor.author | Micallef, Michelle | |
dc.contributor.author | Perram, Jacinta | |
dc.contributor.author | Sockalingam, Sanjeev | |
dc.contributor.author | Dunlop, Adrian J | |
dc.contributor.author | Balcomb, Annie C | |
dc.contributor.author | Day, Carolyn A | |
dc.contributor.author | Treloar, Carla | |
dc.contributor.author | Bath, Nicky | |
dc.contributor.author | Haber, Paul S | |
dc.contributor.author | Dore, Gregory J | |
dc.contributor.author | Grebely, Jason | |
dc.date.accessioned | 2021-11-19T04:48:13Z | |
dc.date.available | 2021-11-19T04:48:13Z | |
dc.date.issued | 2017 | |
dc.identifier.issn | 1932-0620 | en_US |
dc.identifier.doi | 10.1097/ADM.0000000000000261 | en_US |
dc.identifier.uri | http://hdl.handle.net/10072/410259 | |
dc.description.abstract | Objective: The aims of this study were to assess symptoms of depression, anxiety, and stress and associated sociodemographic factors among people living with chronic hepatitis C virus (HCV) infection with a history of injecting drug use and to assess the association between symptoms of depression, anxiety, or stress and HCV treatment intent, specialist assessment, or treatment uptake. Methods: The Enhancing Treatment for Hepatitis C in Opioid Substitution Settings was an observational cohort study evaluating the provision of HCV assessment and treatment among people with chronic HCV and a history of injecting drug use, recruited from 9 community health centers and opioid substitution therapy (OST) clinics (New South Wales, Australia). Symptoms were assessed using the Depression Anxiety Stress Scales (DASS-21). Analyses were performed using logistic regression. Results: Among 415 participants (mean age 41 years, 71% male), 47%, 52%, and 36% demonstrated moderate to extremely severe symptoms of depression, anxiety, and stress, respectively. In adjusted analyses, depression symptoms were associated with recent injecting drug use [adjusted odds ratio (aOR) 1.63, 95% confidence interval (CI) 1.07-2.49), whereas stress symptoms were associated with unemployment (aOR 2.99, 95% CI 1.09-8.15) and not living with a spouse or other relatives/friends (aOR 1.55, 95% CI 1.01-2.39). Symptoms of depression, anxiety, or stress or having a history of treated mental illness were not independently associated with HCV treatment intent, specialist assessment, or treatment uptake. Conclusions: Findings suggest a need for improved interventions and care regarding mental health among people living with chronic HCV with a history of injecting drug use, but suggest that symptoms of depression, anxiety, and stress should not be immediate contraindications to HCV assessment and treatment. | en_US |
dc.description.peerreviewed | Yes | en_US |
dc.language | English | en_US |
dc.publisher | Wolters Kluwer Health | en_US |
dc.relation.ispartofpagefrom | 10 | en_US |
dc.relation.ispartofpageto | 18 | en_US |
dc.relation.ispartofissue | 1 | en_US |
dc.relation.ispartofjournal | Journal of Addiction Medicine | en_US |
dc.relation.ispartofvolume | 11 | en_US |
dc.subject.fieldofresearch | Health services and systems | en_US |
dc.subject.fieldofresearch | Public health | en_US |
dc.subject.fieldofresearchcode | 4203 | en_US |
dc.subject.fieldofresearchcode | 4206 | en_US |
dc.subject.keywords | Science & Technology | en_US |
dc.subject.keywords | Life Sciences & Biomedicine | en_US |
dc.subject.keywords | Substance Abuse | en_US |
dc.subject.keywords | anxiety | en_US |
dc.subject.keywords | depression | en_US |
dc.title | Depression, anxiety, and stress among people with chronic hepatitis C virus infection and a history of injecting drug use in New South Wales, Australia | en_US |
dc.type | Journal article | en_US |
dc.type.description | C1 - Articles | en_US |
dcterms.bibliographicCitation | Fortier, E; Alavi, M; Bruneau, J; Micallef, M; Perram, J; Sockalingam, S; Dunlop, AJ; Balcomb, AC; Day, CA; Treloar, C; Bath, N; Haber, PS; Dore, GJ; Grebely, J, Depression, anxiety, and stress among people with chronic hepatitis C virus infection and a history of injecting drug use in New South Wales, Australia, Journal of Addiction Medicine, 2017, 11 (1), pp. 10-18 | en_US |
dc.date.updated | 2021-11-19T04:45:27Z | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Krahe, Michelle | |