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dc.contributor.authorFortier, Emmanuel
dc.contributor.authorAlavi, Maryam
dc.contributor.authorBruneau, Julie
dc.contributor.authorMicallef, Michelle
dc.contributor.authorPerram, Jacinta
dc.contributor.authorSockalingam, Sanjeev
dc.contributor.authorDunlop, Adrian J
dc.contributor.authorBalcomb, Annie C
dc.contributor.authorDay, Carolyn A
dc.contributor.authorTreloar, Carla
dc.contributor.authorBath, Nicky
dc.contributor.authorHaber, Paul S
dc.contributor.authorDore, Gregory J
dc.contributor.authorGrebely, Jason
dc.date.accessioned2021-11-19T04:48:13Z
dc.date.available2021-11-19T04:48:13Z
dc.date.issued2017
dc.identifier.issn1932-0620en_US
dc.identifier.doi10.1097/ADM.0000000000000261en_US
dc.identifier.urihttp://hdl.handle.net/10072/410259
dc.description.abstractObjective: The aims of this study were to assess symptoms of depression, anxiety, and stress and associated sociodemographic factors among people living with chronic hepatitis C virus (HCV) infection with a history of injecting drug use and to assess the association between symptoms of depression, anxiety, or stress and HCV treatment intent, specialist assessment, or treatment uptake. Methods: The Enhancing Treatment for Hepatitis C in Opioid Substitution Settings was an observational cohort study evaluating the provision of HCV assessment and treatment among people with chronic HCV and a history of injecting drug use, recruited from 9 community health centers and opioid substitution therapy (OST) clinics (New South Wales, Australia). Symptoms were assessed using the Depression Anxiety Stress Scales (DASS-21). Analyses were performed using logistic regression. Results: Among 415 participants (mean age 41 years, 71% male), 47%, 52%, and 36% demonstrated moderate to extremely severe symptoms of depression, anxiety, and stress, respectively. In adjusted analyses, depression symptoms were associated with recent injecting drug use [adjusted odds ratio (aOR) 1.63, 95% confidence interval (CI) 1.07-2.49), whereas stress symptoms were associated with unemployment (aOR 2.99, 95% CI 1.09-8.15) and not living with a spouse or other relatives/friends (aOR 1.55, 95% CI 1.01-2.39). Symptoms of depression, anxiety, or stress or having a history of treated mental illness were not independently associated with HCV treatment intent, specialist assessment, or treatment uptake. Conclusions: Findings suggest a need for improved interventions and care regarding mental health among people living with chronic HCV with a history of injecting drug use, but suggest that symptoms of depression, anxiety, and stress should not be immediate contraindications to HCV assessment and treatment.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherWolters Kluwer Healthen_US
dc.relation.ispartofpagefrom10en_US
dc.relation.ispartofpageto18en_US
dc.relation.ispartofissue1en_US
dc.relation.ispartofjournalJournal of Addiction Medicineen_US
dc.relation.ispartofvolume11en_US
dc.subject.fieldofresearchHealth services and systemsen_US
dc.subject.fieldofresearchPublic healthen_US
dc.subject.fieldofresearchcode4203en_US
dc.subject.fieldofresearchcode4206en_US
dc.subject.keywordsScience & Technologyen_US
dc.subject.keywordsLife Sciences & Biomedicineen_US
dc.subject.keywordsSubstance Abuseen_US
dc.subject.keywordsanxietyen_US
dc.subject.keywordsdepressionen_US
dc.titleDepression, anxiety, and stress among people with chronic hepatitis C virus infection and a history of injecting drug use in New South Wales, Australiaen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dcterms.bibliographicCitationFortier, E; Alavi, M; Bruneau, J; Micallef, M; Perram, J; Sockalingam, S; Dunlop, AJ; Balcomb, AC; Day, CA; Treloar, C; Bath, N; Haber, PS; Dore, GJ; Grebely, J, Depression, anxiety, and stress among people with chronic hepatitis C virus infection and a history of injecting drug use in New South Wales, Australia, Journal of Addiction Medicine, 2017, 11 (1), pp. 10-18en_US
dc.date.updated2021-11-19T04:45:27Z
gro.hasfulltextNo Full Text
gro.griffith.authorKrahe, Michelle


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