dc.contributor.author | Youlden, Danny R | |
dc.contributor.author | Baade, Peter D | |
dc.contributor.author | McBride, Craig A | |
dc.contributor.author | Pole, Jason D | |
dc.contributor.author | Moore, Andrew S | |
dc.contributor.author | Valery, Patricia C | |
dc.contributor.author | Young, Angela | |
dc.contributor.author | Aitken, Joanne F | |
dc.date.accessioned | 2022-03-08T03:12:25Z | |
dc.date.available | 2022-03-08T03:12:25Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 1545-5009 | |
dc.identifier.doi | 10.1002/pbc.29492 | |
dc.identifier.uri | http://hdl.handle.net/10072/411103 | |
dc.description.abstract | BACKGROUND: This study reports cancer incidence and survival among Aboriginal and Torres Strait Islander children and other Australian children, and assesses changes over time. PROCEDURE: Data were from the population-based Australian Childhood Cancer Registry. The study comprised children aged under 15 diagnosed between 1997 and 2016 and with mortality follow-up until 31 December 2017. Incidence trends were analysed using JoinPoint regression. Five-year cancer-specific survival was calculated using the semi-complete approach with survival comparisons made using multivariable flexible parametric models. RESULTS: Aboriginal and Torres Strait Islander children accounted for 506 of 13,299 eligible cases (3.8%). Incidence rates for Aboriginal and Torres Strait Islander children across the study period increased by 2.3% annually (95% confidence interval [CI]: +0.6% to +4.0%) and for other Australian children increased by 0.6% annually (95% CI: +0.3% to +0.9%; p = .05). Nonetheless, cancer incidence was consistently lower for Aboriginal and Torres Strait Islander children, with an incidence rate ratio of 0.73 (95% CI: 0.62-0.85; p < .01) between 2012 and 2016. Survival for Aboriginal and Torres Strait Islander children with solid tumours was 70.6% (95% CI: 62.5%-77.3%) and for other Australian children was 83.5% (95% CI: 82.3%-84.7%; p < .01), with indications of this difference diminishing in recent years. CONCLUSIONS: Improvements in identification, particularly in urban areas, most likely accounts for the greater increase in cancer incidence rates among Aboriginal and Torres Strait Islander children. Examination of data on stage at diagnosis and treatment may provide important insights into survival for children with solid tumours. | |
dc.description.peerreviewed | Yes | |
dc.language | eng | |
dc.publisher | Wiley | |
dc.relation.ispartofpagefrom | e29492 | |
dc.relation.ispartofissue | 4 | |
dc.relation.ispartofjournal | Pediatric Blood & Cancer | |
dc.relation.ispartofvolume | 69 | |
dc.subject.fieldofresearch | Clinical sciences | |
dc.subject.fieldofresearch | Oncology and carcinogenesis | |
dc.subject.fieldofresearch | Paediatrics | |
dc.subject.fieldofresearchcode | 3202 | |
dc.subject.fieldofresearchcode | 3211 | |
dc.subject.fieldofresearchcode | 3213 | |
dc.subject.keywords | Aboriginal and Torres Strait Islander | |
dc.subject.keywords | Australia | |
dc.subject.keywords | childhood cancer | |
dc.subject.keywords | incidence | |
dc.subject.keywords | survival | |
dc.title | Changes in cancer incidence and survival among Aboriginal and Torres Strait Islander children in Australia, 1997-2016 | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dcterms.bibliographicCitation | Youlden, DR; Baade, PD; McBride, CA; Pole, JD; Moore, AS; Valery, PC; Young, A; Aitken, JF, Changes in cancer incidence and survival among Aboriginal and Torres Strait Islander children in Australia, 1997-2016, Pediatric Blood & Cancer, 2021, 69 (4), pp. e29492 | |
dcterms.dateAccepted | 2021-11-11 | |
dc.date.updated | 2021-12-20T03:35:20Z | |
dc.description.version | Accepted Manuscript (AM) | |
gro.rights.copyright | © 2021 Wiley Periodicals Inc. This is the peer reviewed version of the following article: Changes in cancer incidence and survival among Aboriginal and Torres Strait Islander children in Australia, 1997-2016, Pediatric Blood & Cancer, 2021, 69 (4), pp. e29492, which has been published in final form at https://doi.org/10.1002/pbc.29492. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. | |
gro.hasfulltext | Full Text | |
gro.griffith.author | Youlden, Danny R. | |
gro.griffith.author | McBride, Craig | |
gro.griffith.author | Baade, Peter D. | |
gro.griffith.author | Aitken, Joanne | |