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  • Burden of ischemic heart disease and its attributable risk factors in 204 countries and territories, 1990-2019

    Author(s)
    Safiri, Saeid
    Karamzad, Nahid
    Singh, Kuljit
    Carson-Chahhoud, Kristin
    Adams, Cobi
    Nejadghaderi, Seyed Aria
    Almasi-Hashiani, Amir
    Sullman, Mark JM
    Mansournia, Mohammad Ali
    Bragazzi, Nicola Luigi
    Kaufman, Jay S
    Collins, Gary S
    Kolahi, Ali-Asghar
    Griffith University Author(s)
    Singh, Kuljit
    Year published
    2021
    Metadata
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    Abstract
    AIMS: To report the prevalence, deaths, and disability-adjusted life years (DALYs) associated with ischemic heart disease (IHD) and its attributable risk factors in 204 countries and territories from 1990 to 2019, by age, sex, and socio-demographic index (SDI). METHODS AND RESULTS: Ischemic heart disease was defined as acute myocardial infarction (MI) and chronic IHD (angina; asymptomatic IHD following MI). Cause of death ensemble modelling was used to produce fatality estimates. The prevalence of the non-fatal sequalae of IHD was estimated using DisMod MR 2.1. All estimates were presented as counts and age-standardized rates ...
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    AIMS: To report the prevalence, deaths, and disability-adjusted life years (DALYs) associated with ischemic heart disease (IHD) and its attributable risk factors in 204 countries and territories from 1990 to 2019, by age, sex, and socio-demographic index (SDI). METHODS AND RESULTS: Ischemic heart disease was defined as acute myocardial infarction (MI) and chronic IHD (angina; asymptomatic IHD following MI). Cause of death ensemble modelling was used to produce fatality estimates. The prevalence of the non-fatal sequalae of IHD was estimated using DisMod MR 2.1. All estimates were presented as counts and age-standardized rates per 100 000 population. In 2019, IHD accounted for 197.2 million (177.7-219.5) prevalent cases, 9.1 million (8.4-9.7) deaths, and 182.0 million (170.2-193.5) DALYs worldwide. There were decreases in the global age-standardized prevalence rates of IHD [-4.6% (-5.7, -3.6)], deaths [-30.8% (-34.8, -27.2)], and DALYs [-28.6% (-33.3, -24.2)] from 1990 to 2019. In 2019, the global prevalence and death rates of IHD were higher among males across all age groups, while the death rate peaked in the oldest group for both sexes. A negative association was found between the age-standardized DALY rates and SDI. Globally, high systolic blood pressure (54.6%), high low-density lipoprotein cholesterol (46.6%), and smoking (23.9%) were the three largest contributors to the DALYs attributable to IHD. CONCLUSION: Although the global age-standardized prevalence, death, and DALY rates all decreased. Prevention and control programmes should be implemented to reduce population exposure to risk factors, reduce the risk of IHD in high-risk populations, and provide appropriate care for communities.
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    Journal Title
    European Journal of Preventive Cardiology
    DOI
    https://doi.org/10.1093/eurjpc/zwab213
    Note
    This publication has been entered as an advanced online version in Griffith Research Online.
    Subject
    Cardiology (incl. cardiovascular diseases)
    Epidemiology
    Global burden of disease
    Ischemic heart disease
    Risk factor
    Publication URI
    http://hdl.handle.net/10072/411337
    Collection
    • Journal articles

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