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dc.contributor.authorYingchoncharoen, T
dc.contributor.authorNegishi, T
dc.contributor.authorStanton, T
dc.contributor.authorMarwick, TH
dc.date.accessioned2022-01-25T10:06:48Z
dc.date.available2022-01-25T10:06:48Z
dc.date.issued2014
dc.identifier.issn0894-7317
dc.identifier.doi10.1016/j.echo.2014.02.009
dc.identifier.urihttp://hdl.handle.net/10072/411741
dc.description.abstractBackground Increased left ventricular (LV) dimensions are an indication for surgery in patients with asymptomatic mitral regurgitation, but M-mode or two-dimensional measurements have known limitations. The aim of this study was to determine the value of three-dimensional echocardiography in predicting postoperative outcomes after mitral surgery. Methods Sixty-seven patients with severe asymptomatic or minimally symptomatic mitral regurgitation (69% men; mean age, 62 ± 13 years) who underwent mitral valve surgery from January 2010 to December 2011 were studied. In addition to standard echocardiography, baseline three-dimensional echocardiography was performed for accurate quantification of LV size. Patients were followed over a median time of 1 month (interquartile range, 0-8 months) for postoperative development of atrial fibrillation or LV dysfunction. A multivariate regression analysis was performed to identify associations with events. Results Postoperative LV dysfunction developed in 15 patients (22%), and 21 patients (31%) had postoperative atrial fibrillation. There was no association between two-dimensional end-systolic volume index and outcomes (hazard ratio, 1.02; P =.18). Postoperative atrial fibrillation or LV dysfunction was associated with baseline three-dimensional LV end-systolic volume index (hazard ratio, 1.06; 95% confidence interval, 1.04-1.16), independent of age and presence of coronary artery disease. LVESVi ≥ 40 mL/m2 was the best cutoff value to predict postoperative events (sensitivity, 80%; specificity, 85%). After adding LVESVi to a model containing clinical and echocardiographic parameters, net reclassification improvement was 0.27 (95% confidence interval, 0.25-0.29; P =.024). Conclusions LVESVi from three-dimensional echocardiography is an independent predictor of postoperative outcomes in patients with severe mitral regurgitation that is incremental to other clinical and echocardiographic variables. © 2014 by the American Society of Echocardiography.
dc.description.peerreviewedYes
dc.languageeng
dc.publisherElsevier BV
dc.relation.ispartofpagefrom608
dc.relation.ispartofpageto615
dc.relation.ispartofissue6
dc.relation.ispartofjournalJournal of the American Society of Echocardiography
dc.relation.ispartofvolume27
dc.subject.fieldofresearchCardiovascular medicine and haematology
dc.subject.fieldofresearchcode3201
dc.subject.keywordsLV dimensions
dc.subject.keywordsLV volume
dc.subject.keywordsMitral regurgitation
dc.subject.keywordsThree-dimensional echocardiography
dc.subject.keywordsTwo-dimensional echocardiography
dc.titleIncremental value of three-dimensional echocardiography in the evaluation of left ventricular size in mitral regurgitation: A follow-up study after mitral valve surgery
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationYingchoncharoen, T; Negishi, T; Stanton, T; Marwick, TH, Incremental value of three-dimensional echocardiography in the evaluation of left ventricular size in mitral regurgitation: A follow-up study after mitral valve surgery, Journal of the American Society of Echocardiography, 2014, 27 (6), pp. 608-615
dc.date.updated2022-01-25T10:06:00Z
gro.hasfulltextNo Full Text
gro.griffith.authorStanton, Tony


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