dc.contributor.author | Yingchoncharoen, T | |
dc.contributor.author | Negishi, T | |
dc.contributor.author | Stanton, T | |
dc.contributor.author | Marwick, TH | |
dc.date.accessioned | 2022-01-25T10:06:48Z | |
dc.date.available | 2022-01-25T10:06:48Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 0894-7317 | |
dc.identifier.doi | 10.1016/j.echo.2014.02.009 | |
dc.identifier.uri | http://hdl.handle.net/10072/411741 | |
dc.description.abstract | Background Increased left ventricular (LV) dimensions are an indication for surgery in patients with asymptomatic mitral regurgitation, but M-mode or two-dimensional measurements have known limitations. The aim of this study was to determine the value of three-dimensional echocardiography in predicting postoperative outcomes after mitral surgery. Methods Sixty-seven patients with severe asymptomatic or minimally symptomatic mitral regurgitation (69% men; mean age, 62 ± 13 years) who underwent mitral valve surgery from January 2010 to December 2011 were studied. In addition to standard echocardiography, baseline three-dimensional echocardiography was performed for accurate quantification of LV size. Patients were followed over a median time of 1 month (interquartile range, 0-8 months) for postoperative development of atrial fibrillation or LV dysfunction. A multivariate regression analysis was performed to identify associations with events. Results Postoperative LV dysfunction developed in 15 patients (22%), and 21 patients (31%) had postoperative atrial fibrillation. There was no association between two-dimensional end-systolic volume index and outcomes (hazard ratio, 1.02; P =.18). Postoperative atrial fibrillation or LV dysfunction was associated with baseline three-dimensional LV end-systolic volume index (hazard ratio, 1.06; 95% confidence interval, 1.04-1.16), independent of age and presence of coronary artery disease. LVESVi ≥ 40 mL/m2 was the best cutoff value to predict postoperative events (sensitivity, 80%; specificity, 85%). After adding LVESVi to a model containing clinical and echocardiographic parameters, net reclassification improvement was 0.27 (95% confidence interval, 0.25-0.29; P =.024). Conclusions LVESVi from three-dimensional echocardiography is an independent predictor of postoperative outcomes in patients with severe mitral regurgitation that is incremental to other clinical and echocardiographic variables. © 2014 by the American Society of Echocardiography. | |
dc.description.peerreviewed | Yes | |
dc.language | eng | |
dc.publisher | Elsevier BV | |
dc.relation.ispartofpagefrom | 608 | |
dc.relation.ispartofpageto | 615 | |
dc.relation.ispartofissue | 6 | |
dc.relation.ispartofjournal | Journal of the American Society of Echocardiography | |
dc.relation.ispartofvolume | 27 | |
dc.subject.fieldofresearch | Cardiovascular medicine and haematology | |
dc.subject.fieldofresearchcode | 3201 | |
dc.subject.keywords | LV dimensions | |
dc.subject.keywords | LV volume | |
dc.subject.keywords | Mitral regurgitation | |
dc.subject.keywords | Three-dimensional echocardiography | |
dc.subject.keywords | Two-dimensional echocardiography | |
dc.title | Incremental value of three-dimensional echocardiography in the evaluation of left ventricular size in mitral regurgitation: A follow-up study after mitral valve surgery | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dcterms.bibliographicCitation | Yingchoncharoen, T; Negishi, T; Stanton, T; Marwick, TH, Incremental value of three-dimensional echocardiography in the evaluation of left ventricular size in mitral regurgitation: A follow-up study after mitral valve surgery, Journal of the American Society of Echocardiography, 2014, 27 (6), pp. 608-615 | |
dc.date.updated | 2022-01-25T10:06:00Z | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Stanton, Tony | |