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dc.contributor.authorWolski, Marcin
dc.contributor.authorStachowiak, Gwidon W
dc.contributor.authorDempsey, Alasdair R
dc.contributor.authorMills, Peter M
dc.contributor.authorCicuttini, Flavia M
dc.contributor.authorWang, Yuanyuan
dc.contributor.authorStoffel, Karl K
dc.contributor.authorLloyd, David G
dc.contributor.authorPodsiadlo, Pawel
dc.date.accessioned2017-05-03T15:57:06Z
dc.date.available2017-05-03T15:57:06Z
dc.date.issued2011
dc.date.modified2011-10-07T04:28:43Z
dc.identifier.issn0736-0266
dc.identifier.doi10.1002/jor.21396
dc.identifier.urihttp://hdl.handle.net/10072/41185
dc.description.abstractThe objective of this work is to evaluate differences in trabecular bone (TB) texture between subjects with and without tibiofemoral cartilage defects using a variance orientation transform (VOT) method. A case-control study was performed in subjects without radiographic knee osteoarthritis (OA) (K&L grade <2) matched on sex, BMI, age, knee compartment, and meniscectomy where cases (n 젲8) had cartilage defects (grade _2) and controls (n 젲8) had no cartilage defects (grade <2). Cartilage defects were assessed from MRI using validated methods. The VOT was applied to TB regions selected on medial and lateral compartments in knee X-rays and fractal signatures (FS) in the horizontal (FSH) and vertical (FSV) directions, and along the roughest part of TB (FSSta) and texture aspect ratio signatures (StrS), at different trabecular image sizes (0.30-0.70 mm) were calculated. Compared with controls, FSV for cases were higher (p < 0.011) at image sizes 0.30-0.40 mm and 0.45-0.55 mm in the medial compartment. In the lateral compartment, FSH and FSSta for cases were higher (p < 0.028) than those for controls at 0.30-0.40 mm and 0.45-0.55 mm, while FSV was higher (p < 0.02) at 0.30-0.40 mm. TB texture roughness was greater in subjects with cartilage defects than in subjects without, suggesting thinning and fenestration of TB occur early in OA and that the VOT identifies changes in TB in knees with early cartilage damage. No differences in StrS (p > 0.05) were found.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherJonh Wiley & Sons Inc
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationY
dc.relation.ispartofpagefrom1161
dc.relation.ispartofpageto1167
dc.relation.ispartofissue8
dc.relation.ispartofjournalJournal of Orthopaedic Research
dc.relation.ispartofvolume29
dc.rights.retentionY
dc.subject.fieldofresearchBiomedical engineering
dc.subject.fieldofresearchBiomechanical engineering
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchSports science and exercise
dc.subject.fieldofresearchBiomechanics
dc.subject.fieldofresearchcode4003
dc.subject.fieldofresearchcode400303
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode4207
dc.subject.fieldofresearchcode420701
dc.titleTrabecular bone texture detected by plain radiography and variance orientation transform method is different between knees with and without cartilage defects
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2011
gro.hasfulltextNo Full Text
gro.griffith.authorLloyd, David


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