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  • Exercise is medicine? The cardiorespiratory implications of ultra-marathon

    Author(s)
    Tiller, NB
    Stewart, GM
    Illidi, CR
    Levine, BD
    Griffith University Author(s)
    Stewart, Glenn
    Year published
    2020
    Metadata
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    Abstract
    Regular physical activity decreases the risk of cardiovascular disease, type II diabetes, obesity, certain cancers, and all-cause mortality. Nevertheless, there is mounting evidence that extreme exercise behaviors may be detrimental to human health. This review collates several decades of literature on the physiology and pathophysiology of ultra-marathon running, with emphasis on the cardiorespiratory implications. Herein, we discuss the prevalence and clinical significance of postrace decreases in lung function and diffusing capacity, respiratory muscle fatigue, pulmonary edema, biomarkers of cardiac injury, left/right ...
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    Regular physical activity decreases the risk of cardiovascular disease, type II diabetes, obesity, certain cancers, and all-cause mortality. Nevertheless, there is mounting evidence that extreme exercise behaviors may be detrimental to human health. This review collates several decades of literature on the physiology and pathophysiology of ultra-marathon running, with emphasis on the cardiorespiratory implications. Herein, we discuss the prevalence and clinical significance of postrace decreases in lung function and diffusing capacity, respiratory muscle fatigue, pulmonary edema, biomarkers of cardiac injury, left/right ventricular dysfunction, and chronic myocardial remodeling. The aim of this article is to inform risk stratification for ultra-marathon and to edify best practice for personnel overseeing the events (i.e., race directors and medics).
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    Journal Title
    Current Sports Medicine Reports
    Volume
    19
    Issue
    8
    DOI
    https://doi.org/10.1249/JSR.0000000000000738
    Subject
    Cardiovascular medicine and haematology
    Exercise physiology
    Publication URI
    http://hdl.handle.net/10072/412281
    Collection
    • Journal articles

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