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dc.contributor.authorA. Gordon, Catherineen_US
dc.contributor.authorGray, Darrenen_US
dc.contributor.authorGobert, Geoffreyen_US
dc.contributor.authorMcManus, Donen_US
dc.date.accessioned2017-05-03T14:01:27Z
dc.date.available2017-05-03T14:01:27Z
dc.date.issued2011en_US
dc.date.modified2011-10-14T07:14:20Z
dc.identifier.issn0890-8508en_US
dc.identifier.doi10.1016/j.mcp.2011.05.002en_AU
dc.identifier.urihttp://hdl.handle.net/10072/41255
dc.description.abstractParasitic helminths of humans are a major public health threat, particularly in developing countries. The rapid and reliable diagnosis of helminth infections is central to their control as well as for environmental monitoring and disease surveillance. Effective diagnosis is dependent on the sensitivity, specificity and reliability of the tests employed. The most commonly used diagnosis of helminth infections has been the microscopic detection of eggs in faecal samples. However, the eggs of related helminths are often very similar in morphology and morphometry, making diagnosis inaccurate. DNA amplification tests can provide alternative approaches for diagnosis and can be sensitive and specific, provided reliable molecular genetic markers are employed in the tests. Such advanced tools can be used for the quantification of egg numbers, in order to assess infection intensities in infected hosts, and can provide multiplexing capability which can be required for the identification of multiple different helminth species in individual samples. These approaches provide powerful diagnostic techniques that can be used in clinical settings and as laboratory tools for surveillance and for environmental monitoring to support helminth control programs.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherElsevieren_US
dc.publisher.placeUnited Kingdomen_US
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom143en_US
dc.relation.ispartofpageto152en_US
dc.relation.ispartofissue4en_US
dc.relation.ispartofjournalMolecular and Cellular Probesen_US
dc.relation.ispartofvolume25en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchMedical Parasitologyen_US
dc.subject.fieldofresearchcode110803en_US
dc.titleDNA amplification approaches for the diagnosis of key parasitic helminth infections of humansen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2011
gro.hasfulltextNo Full Text


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