Conflict in interpretation of ophthalmic artery Doppler waveform (Reply)

Abstract

We thank Dr Debs Diniz for her appreciation of our systematic review. She is indeed correct to point out that the yellow arrow in supplementary figure 2 of the review corresponds to the systolic phase of the cardiac cycle rather than the diastole phase, and we are grateful for this opportunity to correct the figure. According to the work of Holdsworth et al. on carotid artery Doppler, the diastolic phase of a cardiac cycle starts shortly after the dicrotic notch of the carotid artery Doppler waveform1. The location of the second systolic peak was also shown correctly in recent work by Dr Debs Diniz's group2. Accordingly, the correct version of the supplementary figure 2 is presented here (Figure 1). Nevertheless, it is important to underline that calculation of the peak ratio remains unchanged. We share Dr Debs Diniz's hope that more research investigating the association of ophthalmic artery Doppler with various cardiac manifestations of pre-eclampsia will be carried out in the future3.