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dc.contributor.authorGeorge, Roy
dc.contributor.authorWong, Matthew
dc.contributor.authorJarrett, James
dc.contributor.authorWhite, Alan
dc.contributor.authorWalsh, LaurenceJ
dc.date.accessioned2022-04-05T14:41:49Z
dc.date.available2022-04-05T14:41:49Z
dc.date.issued2021
dc.identifier.issn0972-0707
dc.identifier.doi10.4103/jcd.jcd_432_21
dc.identifier.urihttp://hdl.handle.net/10072/413744
dc.description.abstractAims: This mass spectrometry study investigated the diffusion of hydroxyl and calcium ions from a calcium hydroxide intracanal medicament (Pulpdent®) when used alone or mixed in equal parts with a steroid–antibiotic paste (Ledermix®). Materials and Methods: The pH (using pH meter) and calcium ion concentration (using inductively coupled plasma-mass spectrometry) of the diffused medicaments were assessed using endodontically prepared human extracted teeth with either a sealed or a patent apex, at time intervals of 1, 3, 8, 24, and 168 h. Statistical Analysis: A one-way ANOVA was used to explore differences between and within groups, with Tukey–Kramer/Games–Howell posttests. Results: In both situations tested, Pulpdent® showed greater release of both calcium and hydroxyl ions than when mixed in equal parts with Ledermix®. Greater initial release of both ions occurred in roots with a patent apex, but by 1 week there was no significant difference between the two. If a 50:50 combination of Pulpdent® paste and Ledermix® paste is used, there is a lower release of calcium ions and hydroxyl ions than using Pulpdent® paste alone. Conclusion: With both Pulpdent® paste alone and Pulpdent® paste mixed equally with Ledermix® paste, the major pathway for movement of hydroxyl ions and calcium ions is diffusion through the dentine of the root, with the apex playing only a minor role.
dc.description.peerreviewedYes
dc.languageen
dc.publisherMedknow
dc.relation.ispartofpagefrom611
dc.relation.ispartofpageto611
dc.relation.ispartofissue6
dc.relation.ispartofjournalJournal of Conservative Dentistry
dc.relation.ispartofvolume24
dc.subject.fieldofresearchDentistry
dc.subject.fieldofresearchcode3203
dc.titleEvaluation of the diffusion of calcium hydroxide-based medicaments through the dentinal tubules and apical foramen: A mass spectrometry study
dc.typeJournal article
dc.type.descriptionC1 - Articles
dcterms.bibliographicCitationGeorge, R; Wong, M; Jarrett, J; White, A; Walsh, L, Evaluation of the diffusion of calcium hydroxide-based medicaments through the dentinal tubules and apical foramen: A mass spectrometry study, Journal of Conservative Dentistry, 2021, 24 (6), pp. 611-611
dcterms.licensehttps://creativecommons.org/licenses/by-nc-sa/4.0/
dc.date.updated2022-04-05T04:14:50Z
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2022 Journal of Conservative Dentistry | Published by Wolters Kluwer - Medknow. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution‑NonCommercial‑ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non‑commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
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gro.griffith.authorGeorge, Roy


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