Comparing endurance- and resistance-exercise training in people with multiple sclerosis: a randomized pilot study
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Objective: The purpose of this study was to compare adaptations in functional and quality of life measures following endurance- and resistance-exercise training in people with multiple sclerosis. Design: Cross-over design with an eight-week washout period. Setting: Community health centre. Subjects: Sixteen individuals with multiple sclerosis. Intervention: Subjects completed both an eight-week endurance- and an eight-week resistance-exercise training programme in a randomized order. The exercise training comprised individualized progressive programmes that were completed twice weekly in a supervised group setting. Main measures: Grip strength, functional reach, four step square, timed up and go and six-minute walk tests, Multiple Sclerosis Impact and Modified Fatigue Impact Scales, Becks Depression Inventory and the Health Status Questionnaire Short Form-36. Results: Sixteen of 21 (76%) subjects completed the study. Subjects attended 13.2?.6 endurance- and 15.8?.9 resistance-exercise training sessions. No adverse events were reported. No significant differences (P?<?0.05) in any outcome measures were observed between the two exercise training programmes either at baseline or following the completion of both training programmes. Conclusion: Both endurance- and resistance-exercise training were well tolerated and appear to provide similar effects for people with multiple sclerosis, but larger studies are required to confirm these findings.
© 2011 SAGE Publications. This is the author-manuscript version of the paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
Medical and Health Sciences not elsewhere classified