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dc.contributor.authorPearson, Andrewen_US
dc.contributor.authorKiefel, Miltonen_US
dc.contributor.authorFerro, Vitoen_US
dc.contributor.authorvon Itzstein, Marken_US
dc.date.accessioned2017-05-03T11:05:40Z
dc.date.available2017-05-03T11:05:40Z
dc.date.issued2005en_US
dc.date.modified2009-10-19T05:25:04Z
dc.identifier.issn00086215en_US
dc.identifier.doi10.1016/j.carres.2005.06.029en_AU
dc.identifier.urihttp://hdl.handle.net/10072/4188
dc.description.abstractThis work describes our preliminary efforts towards the development of aryl glucuronides as potential probes for heparanase. During the course of these initial investigations, attempted glycosidation of methyl 2,3,4-tri-O-acetyl-a-d-glucopyranosyluronate trichloroacetimidate with 4-hydroxycinnamic acid gave a complex mixture of four different components. These were identified as the 1-cinnamyl glucuronate ester 13, the cinnamyl linked disaccharide 14, the glucuronate trichloroacetamide 15, and the glucuronyl a-fluoride 16. This paper rationalises the formation of each of these products, and reports our efforts in trying to optimise the formation of the a-fluoride 16.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherElsevier Ltden_US
dc.publisher.placeOxford, Englanden_US
dc.publisher.urihttp://www.elsevier.com/wps/find/journaldescription.cws_home/424829/description#descriptionen_AU
dc.relation.ispartofstudentpublicationYen_AU
dc.relation.ispartofpagefrom2077en_US
dc.relation.ispartofpageto2085en_US
dc.relation.ispartofissue13en_US
dc.relation.ispartofjournalCarbohydrate Researchen_US
dc.relation.ispartofvolume340en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchcode250301en_US
dc.titleTowards the synthesis of aryl glucuronides as potential heparanase probes. An interesting outcome in the glycosidation of glucuronic acid with 4-hydroxycinnamic aciden_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyGriffith Health, School of Medical Scienceen_US
gro.date.issued2005
gro.hasfulltextNo Full Text


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