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dc.contributor.authorCao, Qimingen_US
dc.contributor.authorYu, Jimmyen_US
dc.contributor.authorConnell, Desen_US
dc.date.accessioned2017-05-03T12:06:44Z
dc.date.available2017-05-03T12:06:44Z
dc.date.issued2011en_US
dc.date.modified2012-02-10T01:05:35Z
dc.identifier.issn03043894en_US
dc.identifier.doi10.1016/j.jhazmat.2011.01.054en_US
dc.identifier.urihttp://hdl.handle.net/10072/42261
dc.description.abstractIn health risk assessment, risk is commonly characterised by calculating a simple hazard quotient (HQ), which cannot reflect the actual distribution of exposure and health effect values. This study aimed to develop a new risk characterisation method, the overall risk probability (ORP) method based on probabilistic techniques. Exposure exceedence values were calculated to obtain an exposure exceedence curve (EEC). The area under the EEC was calculated as the ORP value to represent the risk. This method was demonstrated by a case study for two steroidal EDCs, 17߭estradiol (E2) and 17a-ethinylestradiol (EE2) for fish in surface water. It was found that the risk probability of fish exposed to E2 (ORP, 8.1%) and EE2 (ORP, 27%) were both above the reference value of 2.5%, which was consistent with the results of HQ method. Assuming independent action of individual EDCs, a combined risk probability of 33% was obtained for the mixture effects of E2 and EE2. Our results implicated that the adverse health effects imposed by E2 and EE2 were significant for fish in surface water worldwide.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.languageEnglishen_US
dc.language.isoen_US
dc.publisherElsevieren_US
dc.publisher.placeNetherlandsen_US
dc.relation.ispartofstudentpublicationNen_US
dc.relation.ispartofpagefrom480en_US
dc.relation.ispartofpageto487en_US
dc.relation.ispartofissue1-3en_US
dc.relation.ispartofjournalJournal of Hazardous Materialsen_US
dc.relation.ispartofvolume187en_US
dc.rights.retentionYen_US
dc.subject.fieldofresearchEnvironmental Technologiesen_US
dc.subject.fieldofresearchcode090703en_US
dc.titleHealth risk characterisation for environmental pollutants with a new concept of overall risk probabilityen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyGriffith Sciences, Griffith School of Environmenten_US
gro.date.issued2011
gro.hasfulltextNo Full Text


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