An efficient approach to 2,5-anhydro-glucitol-based 1'-homo-N-nucleoside mimetics
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This Letter describes an efficient synthesis of a range of 10-homo-N-nucleoside mimetics with a series of 4-substituted 1,2,3-triazoles replacing the natural nucleobase. The synthesis of 6-O-monosulfated 10- homo-N-nucleoside mimetic derivatives is also discussed.
Organic Chemical Synthesis