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  • Austrocolorone B and austrocolorin B1, cytotoxic anthracenone dimers from the Tasmanian mushroom Cortinarius vinosipes Gasparini

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    Author(s)
    Beattie, Karren D
    Thompson, Dion R
    Tiralongo, Evelin
    Ratkowsky, David
    May, Tom W
    Gill, Melvyn
    Griffith University Author(s)
    Tiralongo, Evelin
    Mitchell, Karren D.
    Year published
    2011
    Metadata
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    Abstract
    The yellow dihydroanthracenone dimer, austrocolorin B1 and the unique violet-red 1,4-anthraquinone dimer, austrocolorone B, were isolated from the Tasmanian mushroom Cortinarius vinosipes and their structures and stereochemistry were determined from spectroscopic data. Austrocolorin B1 and austrocolorone B were found to exhibit potent cytotoxic activity in vitro against the murine lymphoblast (P388D1) cell line with IC50 values in the range 10-31 ug/mL.The yellow dihydroanthracenone dimer, austrocolorin B1 and the unique violet-red 1,4-anthraquinone dimer, austrocolorone B, were isolated from the Tasmanian mushroom Cortinarius vinosipes and their structures and stereochemistry were determined from spectroscopic data. Austrocolorin B1 and austrocolorone B were found to exhibit potent cytotoxic activity in vitro against the murine lymphoblast (P388D1) cell line with IC50 values in the range 10-31 ug/mL.
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    Journal Title
    Tetrahedron Letters
    Volume
    52
    Issue
    42
    DOI
    https://doi.org/10.1016/j.tetlet.2011.08.015
    Copyright Statement
    © 2011 Elsevier. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
    Subject
    Natural Products Chemistry
    Medicinal and Biomolecular Chemistry
    Organic Chemistry
    Publication URI
    http://hdl.handle.net/10072/42920
    Collection
    • Journal articles

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