Austrocolorone B and austrocolorin B1, cytotoxic anthracenone dimers from the Tasmanian mushroom Cortinarius vinosipes Gasparini

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Author(s)
Beattie, Karren D
Thompson, Dion R
Tiralongo, Evelin
Ratkowsky, David
May, Tom W
Gill, Melvyn
Griffith University Author(s)
Year published
2011
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Abstract
The yellow dihydroanthracenone dimer, austrocolorin B1 and the unique violet-red 1,4-anthraquinone dimer, austrocolorone B, were isolated from the Tasmanian mushroom Cortinarius vinosipes and their structures and stereochemistry were determined from spectroscopic data. Austrocolorin B1 and austrocolorone B were found to exhibit potent cytotoxic activity in vitro against the murine lymphoblast (P388D1) cell line with IC50 values in the range 10-31 ug/mL.
Journal Title
Tetrahedron Letters
Volume
52
Issue
42
DOI
Copyright Statement
© 2011 Elsevier. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
Subject
Natural Products Chemistry
Medicinal and Biomolecular Chemistry
Organic Chemistry
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