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dc.contributor.authorLevonis, Stephanen_US
dc.contributor.authorKiefel, Miltonen_US
dc.contributor.authorHouston, Todden_US
dc.date.accessioned2017-05-03T13:55:46Z
dc.date.available2017-05-03T13:55:46Z
dc.date.issued2011en_US
dc.date.modified2012-02-17T05:13:33Z
dc.identifier.issn00049425en_US
dc.identifier.doi10.1071/CH11296en_US
dc.identifier.urihttp://hdl.handle.net/10072/42926
dc.description.abstractA self-assembling fluorescence sensor with boronic acid functionalities was tested for binding selectivity to the monosaccharide, sialic acid. Working from a previously reported system, a self-assembling system could form an imine in situ that enables a conjugated fluorophore to display a measurable change in fluorescence in the presence of monosaccharide. However, further examination showed that free sugars give a similar fluorescence response to just the m-aminophenylboronic acid moiety on its own. Still, such a self-assembly method may be applicable to cell surface saccharide sensing as aldehydes and ketones are noticeably absent on most cells' exteriors. The original covalent receptor appears best suited for the detection of free sialic acid.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.languageEnglishen_US
dc.publisherCSIRO Publishingen_US
dc.publisher.placeAustraliaen_US
dc.relation.ispartofstudentpublicationYen_US
dc.relation.ispartofpagefrom1454en_US
dc.relation.ispartofpageto1457en_US
dc.relation.ispartofissue11en_US
dc.relation.ispartofjournalAustralian Journal of Chemistryen_US
dc.relation.ispartofvolume64en_US
dc.rights.retentionNen_US
dc.subject.fieldofresearchOrganic Chemistry not elsewhere classifieden_US
dc.subject.fieldofresearchcode030599en_US
dc.titleComparing Self-Assembling and Covalent Fluorescent Boronolectins for the Detection of Free Sialic Aciden_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyOffice of the Snr Dep Vice Chancellor, Institute for Glycomicsen_US
gro.date.issued2011
gro.hasfulltextNo Full Text


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