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dc.contributor.authorDevakaram, Ruth
dc.contributor.authorBlack, David StC
dc.contributor.authorAndrews, Katherine T
dc.contributor.authorFisher, Gillian M
dc.contributor.authorDavis, Rohan A
dc.contributor.authorKumar, Naresh
dc.date.accessioned2018-04-03T22:15:31Z
dc.date.available2018-04-03T22:15:31Z
dc.date.issued2011
dc.date.modified2012-03-01T22:10:20Z
dc.identifier.issn0968-0896
dc.identifier.doi10.1016/j.bmc.2011.07.009
dc.identifier.urihttp://hdl.handle.net/10072/43207
dc.description.abstract7-Methoxyflavenes and 5,7,8-trimethoxyflavenes were found to undergo stereoselective acid-catalyzed rearrangement to generate the benzopyrano[4,3-b]benzopyran ring system present in the natural product, dependensin. Dependensin and its analogs were subjected to antimalarial growth inhibition assays against Plasmodium falciparum and found to have IC50 values ranging between 1.9 and 3.9 μM.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.publisherElsevier
dc.publisher.placeUnited Kingdom
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom5199
dc.relation.ispartofpageto5206
dc.relation.ispartofissue17
dc.relation.ispartofjournalBioorganic & Medicinal Chemistry
dc.relation.ispartofvolume19
dc.rights.retentionY
dc.subject.fieldofresearchInfectious Agents
dc.subject.fieldofresearchMedicinal and Biomolecular Chemistry
dc.subject.fieldofresearchOrganic Chemistry
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciences
dc.subject.fieldofresearchcode060502
dc.subject.fieldofresearchcode0304
dc.subject.fieldofresearchcode0305
dc.subject.fieldofresearchcode1115
dc.titleSynthesis and antimalarial evaluation of novel benzopyrano[4,3-b]benzopyran derivatives
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2011
gro.hasfulltextNo Full Text
gro.griffith.authorAndrews, Katherine T.
gro.griffith.authorDavis, Rohan A.
gro.griffith.authorFisher, Gill M.


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