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dc.contributor.authorNewton, Melissaen_US
dc.contributor.authorHayes, Sandien_US
dc.contributor.authorJanda, Monikaen_US
dc.contributor.authorWebb, Penelopeen_US
dc.contributor.authorObermair, Andreasen_US
dc.contributor.authorEakin, Elizabethen_US
dc.contributor.authorWyld, Daviden_US
dc.contributor.authorGordon, Louisaen_US
dc.contributor.authorBeesley, Vanessaen_US
dc.date.accessioned2017-04-24T11:36:16Z
dc.date.available2017-04-24T11:36:16Z
dc.date.issued2011en_US
dc.date.modified2012-03-08T22:18:21Z
dc.identifier.issn1471-2407en_US
dc.identifier.doi10.1186/1471-2407-11-389en_US
dc.identifier.urihttp://hdl.handle.net/10072/43426
dc.description.abstractBackground Exercise interventions during adjuvant cancer therapy have been shown to increase functional capacity, relieve fatigue and distress and may assist rates of chemotherapy completion. These studies have been limited to breast, gastric and mixed cancer groups and it is not yet known if a similar intervention is even feasible among women with ovarian cancer. We aimed to assess safety, feasibility and potential effect of a walking intervention in women undergoing chemotherapy for ovarian cancer. Methods Women newly diagnosed with ovarian cancer were recruited to participate in an individualised walking intervention throughout chemotherapy and were assessed pre- and post-intervention. Feasibility measures included session adherence, compliance with exercise physiologist prescribed walking targets and self-reported program acceptability. Changes in objective physical functioning (6-minute walk test), self-reported distress (Hospital Anxiety and Depression Scale), symptoms (Memorial Symptom Assessment Scale - Physical) and quality of life (Functional Assessment of Cancer Therapy - Ovarian) were calculated, and chemotherapy completion and adverse intervention effects recorded. Results Seventeen women were enrolled (63% recruitment rate). Mean age was 60 years (SD = 8 years), 88% were diagnosed with FIGO stage III or IV disease, 14 women underwent adjuvant and three neo-adjuvant chemotherapy. On average, women adhered to > 80% of their intervention sessions and complied with 76% of their walking targets, with the majority walking four days a week at moderate intensity for 30 minutes per session. Meaningful improvements were found in physical functioning, physical symptoms, physical well-being and ovarian cancer-specific quality of life. Most women (76%) completed =85% of their planned chemotherapy dose. There were no withdrawals or serious adverse events and all women reported the program as being helpful.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.format.extent1524943 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglishen_US
dc.publisherBioMed Centralen_US
dc.publisher.placeUnited Kingdomen_US
dc.relation.ispartofstudentpublicationNen_US
dc.relation.ispartofpagefrom389-1en_US
dc.relation.ispartofpageto389-9en_US
dc.relation.ispartofissue9en_US
dc.relation.ispartofjournalBMC Canceren_US
dc.relation.ispartofvolume11en_US
dc.rights.retentionYen_US
dc.subject.fieldofresearchMedical and Health Sciences not elsewhere classifieden_US
dc.subject.fieldofresearchcode119999en_US
dc.titleSafety, feasibility and effects of an individualised walking intervention for women undergoing chemotherapy for ovarian cancer: a pilot studyen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.rights.copyrightCopyright 2011, http://dx.doi.org/10.1186/1471-2407-11-389 et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
gro.date.issued2011
gro.hasfulltextFull Text


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